Internal Medicine
RSSArticles
-
Corticosteroid Bursts and Subsequent Sepsis
Short-term (< 14 days) administration of oral corticosteroids is associated with an increased risk of adverse events, including an approximately two-fold risk of sepsis.
-
First There Was MIS-C, Now There Is MIS-A
Multisystem inflammatory syndrome in adults (MIS-A), similar to multisystem inflammatory syndrome in children (MIS-C), is described by the Centers for Disease Control and Prevention.
-
Ethical Issues Affecting COVID-19 Vaccination
The world waits eagerly for a COVID-19 vaccine. But the supply of vaccine is unlikely to initially meet the demand. Ethical issues are important as individuals and groups are prioritized for early vaccination.
-
Targeting 100% or 70% of Enteral Calorie Requirements During Critical Illness Results in Equivalent Outcomes at Six Months
This was a multicenter, blinded, parallel-group, randomized trial of mechanically ventilated critically ill patients. Achieving 100% calorie requirements did not change outcomes at six months when compared to a more modest goal of 70% of predicted calorie requirements.
-
Evaluation and Treatment of Severe Community-Acquired Pneumonia in the ICU
Community-acquired pneumonia is a common cause for hospital admission. This article serves to summarize new updates in the definition, prognosis, and treatment, specifically of bacterial, severe community-acquired pneumonia.
-
U.S. Readmission Rates for TAVR
An analysis of the Nationwide Readmission Database revealed one-fifth of transcatheter aortic valve replacement patients are readmitted a median of 31 days after discharge. Medical comorbidities are the most common reason.
-
TAVR Outcomes in Patients on Chronic Corticosteroid Therapy
A 12-year experience with transcatheter aortic valve replacement at one Paris hospital demonstrated chronic systemic corticosteroid use increases the incidence of major 30-day complications and all-cause mortality at one year.
-
When Is TAVR Futile?
A study of all patients who underwent transcatheter aortic valve replacement over eight years in France was used to develop a futility score that would help predict who would not live one year after the procedure. This simple clinical score based on comorbidities predicted who would live one year with 95% specificity.
-
Ticagrelor in the Elderly: More Potent Platelet Inhibition Not Always Better
In a study of 14,000 elderly patients with acute myocardial infarction, treatment with ticagrelor was associated with higher risks of bleeding and all-cause death vs. clopidogrel.
-
Which Acute Myocardial Infarction Patients Need a Blood Transfusion?
A randomized trial of a restrictive blood transfusion strategy vs. a more liberal strategy in patients with acute myocardial infarction and anemia showed the restrictive strategy is noninferior to the liberal strategy for preventing the primary outcome of death, reinfarction, stroke, or emergency revascularization.