Internal Medicine
RSSArticles
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IqYmune for CIDP
IqYmune is a highly purified 10% concentration of human immunoglobulin obtained from healthy volunteers. It appears to have similar efficacy in the treatment of chronic inflammatory demyelinating polyneuropathy (CIDP) as conventional intravenous immunoglobulin, with 76% of the study patients showing a significant improvement in a standardized disability score.
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COVID-19 Infection in MS Patients
In a multicenter, retrospective analysis of patients in a multiple sclerosis (MS) registry, the authors described the clinical characteristics and risks associated with severity of complications from COVID-19 infection in patients with MS.
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Ketamine for Super-Refractory Status Epilepticus
In this retrospective paper, the authors review the efficacy and safety of ketamine infusion in patients with status epilepticus who have failed benzodiazepine, standard anticonvulsant, and at least one other anesthetic drip.
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Mozart Therapy for Epilepsy
A randomized, controlled, crossover trial in adult patients with drug-resistant epilepsy compared listening to a Mozart piano sonata daily to an active control. It showed reduction in seizures during the Mozart treatment compared to both baseline and the control treatment.
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Scrambler Therapy for Neuromyelitis Optica Pain Treatment
Scrambler therapy appears to significantly reduce central neuropathic pain for patients with neuromyelitis optica spectrum disorder, although pain reduction is not shown to be sustained for more than 30 days after treatment.
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Diagnosis and Management of Supraventricular Tachycardia
Supraventricular tachycardia (SVT) is a common medical condition. Diagnosis and treatment often occur simultaneously. To a great degree, long-term treatment options depend on the history of symptoms and the patient’s desire, rather than on the specific type of SVT.
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Infectious Disease Alert Updates
Sex in the Time of COVID-19; Serum SARS-CoV-2 and Disease Severity; Natural History of Untreated Tuberculosis
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Gut Microbiome in Patients at Risk for Parkinson’s Disease
Certain risk factors and prodromal markers of Parkinson’s disease (PD), such as constipation and rapid eye movement sleep behavior disorder, are associated with specific bacterial compositions of the gut. However, the value of gut microbiome data to predict the risk of PD development needs further investigation.
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Hospitalized COVID-19 Patients: SARS-CoV-2 RNA in Plasma Associated with ICU Admission and Mortality
A prospective cohort study found that SARS-CoV-2 plasma RNA was detected more often, and the levels were higher, in patients who were admitted to the intensive care unit and/or who died.
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Chronic Low-Dose Corticosteroids and Infection Risk
The prolonged use of low-dose oral corticosteroids (including < 5 mg prednisone equivalent doses) in rheumatoid arthritis patients is associated with an increased risk of infection.