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The decision to choose a mechanical or a tissue valve for patients undergoing surgical aortic valve replacement (AVR) is a complex one that involves synthesizing clinical factors such as risk of bleeding, likelihood of reoperation, and patient preference. Increasingly, older patients with more comorbidities are being referred for AVR surgery.
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Many patients need to take long-term oral anticoagulants (OAC) for indications such as atrial fibrillation (AF) or mechanical prosthetic valves.
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Guideline-driven earlier mitral valve repair for patients with mitral regurgitation (MR) due to degenerative disease has increased in the last 25 years.
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Beta-blockers and noncardiac surgery; prenatal medication exposure and risk of autism; reasons for statin discontinuations; and FDA actions.
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Patients seen in emergency departments (ED) for acute chest pain who are deemed low risk for acute coronary syndrome (ACS) and relatively safe for discharge are often referred to their primary care physician (PCP) for follow-up.
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The Atrial Fibrillation Follow-up Investigation of Rhythm Management (AFFIRM) trial was completed more than 10 years ago.
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The Biventricular vs Right Ventricular Pacing in Heart Failure Patients with Atrioventricular Block (BLOCK HF) trial tested the hypothesis that biventricular pacing (cardiac resynchronization therapy [CRT]) would be superior to right ventricular pacing in patients with mild-to-moderate heart failure, left ventricular systolic dysfunction, and an indication for full-time ventricular pacing.
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Zolpidem and risk of falls; AVR and anticoagulation; statins in cancer patients; and FDA actions.