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Special Report from the International Stroke Conference: Current Endovascular Interventions for Acute Ischemic Stroke Do Not Result in Better Clinical Outcomes than Intravenous Thrombolysis
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Zolpidem, a commonly utilized agent for sleep disturbance, is associated with increased fall risk in hospitalized, non-pregnant, non-critically ill patients. Its use for a given patient and its appropriateness within standard order sets should be carefully considered.
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During family discussions, physicians who believe more strongly that life support should be withdrawn are more likely to present the option of comfort care and describe its benefits.
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This paper details the result of a population-based cohort study of all Ontario, Canada, residents older than 66 years of age who began warfarin therapy for atrial fibrillation over an 11-year period. Patients were identified by the authors from data in the Ontario Health Insurance Plan.
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In an observational study conducted in Germany of more than 600 anemic cancer patients receiving parenteral iron (ferric carboxymaltose), hemoglobin levels were shown to rise significantly. The iron treatment was well tolerated. Randomized interventional studies are warranted to demonstrate efficacy in terms of physical function and quality of life and safety in this population.
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Osteoarthritis (OA) can be described as the failed repair of damage that has been caused by excessive mechanical stress (defined as force/unit area) on joint tissues.1 This implies that although multiple factors may lead to OA, mechanical impact (either as a major single event or as repetitive micro trauma) is central to all of these, and that the sequence of events that ensues represents the intrinsic repair process, which may either fail or be successful in restoring joint function. Also known as osteoarthrosis or degenerative joint disease, OA is the most important chronic musculoskeletal disorder in both humans and horses.
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Zolpidem and risk of falls; AVR and anticoagulation; statins in cancer patients; and FDA actions.