Internal Medicine
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Prior Metformin Use in Patients with Diabetes Hospitalized for COVID-19
Investigators found metformin use before COVID-19 hospitalization for patients with diabetes was associated with a lower risk of death.
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New Risk Factors for Atherosclerosis
An analysis of the Women’s Health Study based on a recent questionnaire about adverse pregnancy outcomes showed hypertensive disorders of pregnancy and low birth weight are independent predictors of subsequent atherosclerotic cardiovascular disease.
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Can Antioxidant Intake Prevent Coronary Artery Disease?
A study of single nucleotide polymorphisms (SNP) that increase blood levels of diet-derived antioxidants in three large individual subject genetic databases did not demonstrate a relationship between SNPs and coronary artery disease.
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Are Beta-Blockers Still Relevant After a Myocardial Infarction?
A large, contemporary, nationwide, observational study of post-myocardial infarction beta-blocker administration shows that after three months, there were no beneficial effects on adverse cardiovascular events to continued beta-blocker use.
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Statins and Muscle Symptoms: Cause and Effect?
An analysis of three large simvastatin trials revealed muscle symptoms on simvastatin are common, but true myopathy is rare and can be predicted by evaluating certain risk factors for its development, which can help guide patient management.
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Is Effective Transcatheter Tricuspid Repair Becoming a Reality?
In two trials of transcatheter devices treating tricuspid regurgitation, the authors observed high efficacy and low adverse event rates.
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Why Is There Group Beating?
The ECG in the figure was obtained from a 40-year-old man with an irregular heartbeat. How would one interpret this rhythm?
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Relugolix Tablets (Orgovyx)
Relugolix should be prescribed to adults with advanced prostate cancer.
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Prophylactic PCI for Vulnerable Plaques
In this proof-of-concept trial, treatment of non-flow limiting vulnerable plaque by PCI with bioabsorbable stents resulted in no significant difference in lesion-related events compared with optimal medical therapy.
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Does MRSA Nares Colonization Predict Non-Respiratory MRSA Infections?
Nares screening for methicillin-resistant Staphylococcus aureus (MRSA) carried a high negative predictive value to rule out MRSA infections at various sites.