Internal Medicine Alert
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Chest Pain and Giant T Wave Inversion
Chest pain (rather than shortness of breath) and ST elevation (rather than T wave inversion) in leads V1 and V2 make massive pulmonary embolism unlikely.
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Clinical Briefs
In this section: the insulin misadministration problem; comparing smoking cessation pharmacotherapies; more support for ambulatory BP monitoring.
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Tenofovir Alafenamide vs Tenofovir Disoproxil Fumarate
Tenofovir alafenamide has replaced the tenofovir disoproxil fumarate component of two commonly used drug combinations for HIV-1 infection.
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ICH May Clinically Mimic TIA
In a large retrospective review of 2137 patients with intracerebral hemorrhage, 34 presented with transient symptoms that could have been misclassified as “transient ischemic attack” if brain imaging had not been performed.
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Selecting Patients for Statin Primary Prevention
The new vascular disease risk calculator discriminates who will experience a vascular event in the near future better than using a trial entry criteria approach or a hybrid approach.
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Is Anticoagulant Bridging Needed in Patients with Atrial Fibrillation Going to Surgery?
In patients with atrial fibrillation who had warfarin treatment interrupted for an elective operation or other elective invasive procedure, forgoing bridging anticoagulation was not inferior to perioperative bridging with low molecular weight heparin for the prevention of arterial thromboembolism and decreased the risk of major bleeding.
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Clinical Briefs
In this section: a better way to measure blood pressure; the magical powers of grapefruit juice; and yet another reason to stop smoking.
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Coagulation Factor IX (Recombinant), Albumin Fusion Protein
This product is indicated for on-demand control and prevention of bleeding episodes, perioperative management of bleeding, or routine prophylaxis to prevent or reduce the frequency of bleeding episodes in children and adults with hemophilia B (congenital factor IX deficiency).
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Prescient Warning Symptoms: A New Target for Sudden Cardiac Death Prevention
Typical cardiac symptoms frequently precede sudden cardiac arrest and are frequently unheeded, but when acted on are associated with decreased mortality.
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Eat Less Sugar: The New National Dietary Guidelines
A strict adherence to a lower sugar intake may improve the incidences of type 2 diabetes and cardiovascular disease, but the guidelines could have, and should have, gone much further to apply the latest research to promoting dietary change in the United States.