Internal Medicine Alert
RSSArticles
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Clinical Briefs
In this section: comparing blood pressure monitoring techniques; DPP4 agents and heart failure; identifying at-risk groups for hypoglycemia.
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Infliximab-dyyb for Injection (Inflectra)
Infliximab-dyyb offers another, possibly less expensive, option for treatment of a number of autoimmune conditions.
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Early Chest CT Can Improve Treatment for Community-acquired Pneumonia
In patients with suspected community-acquired pneumonia, early chest CT significantly changed management decisions.
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Trimethoprim-sulfamethoxazole vs. Placebo for Skin Abscesses After Incision and Drainage
A multicenter, double-blind, randomized, clinical trial found that a seven-day course of trimethoprim-sulfamethoxazole following incision and drainage (I&D) resulted in a higher rate of cure for skin abscesses compared to I&D and placebo.
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Association of Seafood Consumption and Brain Mercury Levels with Brain Neuropathology
Although moderate seafood consumption was correlated with higher brain levels of mercury, these levels were not correlated with brain neuropathology.
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Clinical Briefs
In this section: examining autoimmune disorders associated with vitiligo; moderate alcohol consumption is not associated with reduced all-cause mortality; and rethinking the American diet.
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Ixekizumab Injection (Taltz)
Ixekizumab is indicated for the treatment of adults with moderate-to-severe plaque psoriasis who are candidates for systemic therapy or phototherapy.
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Outcome of PCSK9 Inhibitor-treated Patients
In a meta-analysis of 17 studies, proprotein convertase subtilisin-kexin type 9 serine protease inhibitors markedly reduced low-density lipoprotein cholesterol levels and all-cause mortality, but was associated with a significant increase in neurocognitive adverse events.
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Menopausal Hormone Therapy: Useful and Indicated for Vasomotor Symptoms
Menopausal hormone therapy is the most effective treatment for symptoms of the menopause, and benefits may exceed risks for most women within 10 years of menopause.
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Drug-resistant Hypertension? Consider Adding a Nonpharmacologic Prescription
In patients with obstructive sleep apnea and hypertension, continuous positive airway pressure use was associated with clinically and statistically significant reductions in blood pressure for both resistant and non-resistant hypertension.