Internal Medicine Alert
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Reducing Cardiovascular Events in Older Adults Through Blood Pressure Control
Among ambulatory adults ≥ 75 years of age, treating to a systolic blood pressure (SBP) target of < 120 mmHg compared with an SBP target of < 140 mmHg resulted in a significantly lower rate of fatal and nonfatal major cardiovascular events and death from any cause.
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Clinical Briefs
In this section:
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Sofosbuvir and Velpatasvir Tablets (Epclusa)
Sofosbuvir and velpatasvir tablets are indicated for the treatment of adult patients with chronic HCV genotype 1, 2, 3, 4, 5, or 6 infections.
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Reduced Cardiac Index Is Not Correlated with Renal Function in Heart Failure Patients
In a retrospective analysis of patients with acute decompensated heart failure who received a pulmonary artery catheter, there was no significant correlation between cardiac index and markers of renal function, contradicting the importance of cardiac output in renal dysfunction among patients with heart failure.
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Should Lipid Measurements Be Obtained in the Fasting or Nonfasting State?
When attempting to determine whether fasting or nonfasting lipid measurements are most appropriate in an individual patient, it is important to first think carefully about the clinical scenario and consider what question the results answer.
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Can a Brain Condition Affect the Heart?
A large, prospective cohort study in women with more than two decades of follow-up indicated a consistent link between migraine and cardiovascular disease events, including cardiovascular mortality.
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Is This ECG Normal for Age?
The seemingly tall lateral chest lead R waves are not outside the normal range for a child this age.
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Clinical Briefs
In this section: effects of testosterone treatment in older men; liraglutide safety and efficacy in patients with non-alcoholic steatohepatitis; and long-acting anticholinergics and beta agonists for COPD.
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Daclizumab Injection (Zinbryta)
Another option for the treatment of the relapsing form of multiple sclerosis.
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The Current Outlook for Cardiac Tamponade
In the modern era, cardiac tamponade is most commonly caused by malignancies with poor prognosis. As compared to older literature, iatrogenic causes have increased, most resulting from complications of percutaneous coronary intervention.