Internal Medicine Alert
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The Zoster Vaccine Rapidly Loses Effectiveness in Adults Over 60
An observational study showed that while the shingles vaccine reduces the risk of herpes zoster, there is a major decline in effectiveness over just eight years in older adults.
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Integrative Treatment for Restless Legs Syndrome: What Does the Evidence Say?
Medical evidence supports the use of physical activity and iron supplementation (for those with low serum ferritin) in patients presenting with restless legs syndrome.
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Influence of Sacubitril/Valsartan on 30-day Readmission After Heart Failure Hospitalization
Compared with enalapril, treatment with sacubitril/valsartan is more effective in reducing 30-day readmissions for any cause following discharge from congestive heart failure hospitalization.
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Acute STEMI or False Alarm?
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Clinical Briefs
In this section: antiretroviral therapy in HIV patients; comparing ticagrelor against aspirin in stroke patients; and weighing the many type 2 diabetes treatments.
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Lifitegrast Ophthalmic Solution (Xiidra)
Lifitegrast is approved for the treatment of the signs and symptoms of dry eye disease.
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Which Patients with TIA Are at High Risk for Recurrent Cerebral Vascular Events?
The objective of this study was to determine predictors of early recurrent cerebral vascular events among patients with transient ischemic attacks or minor stroke.
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Predictive Accuracy of the New Risk Equation
In a large real-world population, the Pooled Cohort Risk Equation substantially overestimated five-year risk of cardiovascular events in adults without diabetes.
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Improving Blood Pressure Through Enhanced Sleep
The use of a benzodiazepine hypnotic among hypertensive patients was associated with improvements in both sleep scores and blood pressure.
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Clinical Briefs
In this section: debunking an asthma treatment; more questions than answers with perioperative statin treatment; and another reason to stay away from cocaine.