Internal Medicine Alert
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Etanercept-szzs Injection (Erelzi)
Etanercept-szzs is indicated for moderate to severe active rheumatoid arthritis, moderate to severe active polyarticular juvenile idiopathic arthritis, psoriatic arthritis, active ankylosing spondylitis, and chronic moderate to severe plaque psoriasis.
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Calcium Supplementation and Increased Dementia Risk
In this five-year observational study, women who were taking calcium supplementation and who presented with pre-existing cerebrovascular disease were at higher risk of dementia than women not taking extra calcium.
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Screening for Coronary Artery Disease Is Underused in Heart Failure
In a large retrospective cohort of patients hospitalized for new-onset heart failure, the majority did not receive testing for ischemic heart disease.
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How Much More Physical Activity Helps Patients Avoid Chronic Diseases?
Higher levels of total physical activity are strongly associated with lower risk of five common chronic diseases: breast and bowel cancer, diabetes, heart disease, and stroke.
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Clinical Briefs
In this section: A game-changing blood pressure trial; new colorectal cancer screening recommendations; and predicting opioid abuse and dependence.
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Oxycodone HCl and Naltrexone HCl Extended-release Capsules (Troxyca ER)
The combination oxycodone/naltrexone is indicated for the management of pain severe enough to require daily, around-the-clock, long-term opioid treatment and for which alternative treatment options are inadequate.
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Association of Traumatic Brain Injury with Late-life Neurodegenerative Diseases
Concern has been raised about an increased risk of Alzheimer’s disease, Parkinson’s disease, and other dementias following traumatic brain injury.
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The Zoster Vaccine Rapidly Loses Effectiveness in Adults Over 60
An observational study showed that while the shingles vaccine reduces the risk of herpes zoster, there is a major decline in effectiveness over just eight years in older adults.
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Integrative Treatment for Restless Legs Syndrome: What Does the Evidence Say?
Medical evidence supports the use of physical activity and iron supplementation (for those with low serum ferritin) in patients presenting with restless legs syndrome.
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Influence of Sacubitril/Valsartan on 30-day Readmission After Heart Failure Hospitalization
Compared with enalapril, treatment with sacubitril/valsartan is more effective in reducing 30-day readmissions for any cause following discharge from congestive heart failure hospitalization.