Internal Medicine Alert
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Glucose Self-monitoring Not Helpful for Non-insulin-treated Type 2 Diabetes
In this pragmatic randomized trial, self-monitoring blood glucose did not lead to lower hemoglobin A1c levels or improvement in health-related quality-of-life measures.
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Clinical Briefs
In this section: blood pressure readings for high-risk hypertension patients; Omega-3 fatty acids and diabetic retinopathy; and long-term diabetes control.
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Betrixaban Capsules (Bevyxxa)
Betrixaban is indicated for the prophylaxis of venous thromboembolism (VTE) in adult patients hospitalized for an acute medical illness who are at risk for thromboembolic complications because of moderate or severe restricted mobility and other risk factors for VTE.
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Omega-3 Polyunsaturated Fatty Acid Supplementation and Cognitive Decline
As the first large randomized, placebo-controlled trial studying the efficacy of a lifestyle intervention with a nutraceutical compound (polyunsaturated fatty acid), the Multidomain Alzheimer Preventive Trial is a landmark study.
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B-type Natriuretic Peptide Is Less Useful in Elderly Patients With Dyspnea
Among patients ≥ 80 years of age presenting with acute dyspnea, B-type natriuretic peptide level was not useful for differentiating cardiac vs. respiratory etiologies when added to a model of clinical predictors.
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Advance Care Planning Must Advance Forward
Advance care planning is a continual process of preparing for future medical care in case patients are unable to make his or her own decisions. It includes engaging patients and families to reflect on patients’ personal goals, values, and belief systems, which ultimately translate into informing medical care. This process helps prepare the patient for current and future decisions regarding medical treatment. Data show that Americans have fallen behind on this process.
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Atrial Flutter or Atrial Tachycardia?
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Clinical Briefs
In this section: nonsteroidal anti-inflammatory drugs and gastrointestinal bleeding; rheumatoid arthritis; and community-acquired pneumonia.
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Delafloxacin Tablets (Baxdela)
Delafloxacin is indicated for the treatment of acute bacterial skin and skin structure infections caused by susceptible organisms.
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Atypical Transient Symptoms Require Aggressive Investigation for Cause
Atypical transient symptoms, such as partial sensory deficit, dysarthria, vertigo and unsteadiness, unusual visual deficits, and diplopia, usually are not classified as transient ischemic attacks, and they frequently are not investigated in the same fashion.