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Pitolisant Tablets (Wakix)

Pitolisant should be prescribed to treat excessive daytime sleepiness in adult patients with narcolepsy.

When Did You Last Take an Antibiotic?

Approximately half of U.S. residents with health insurance filled an antibiotic prescription over a two-year period.

Risk of Neuropathy With Fluoroquinolones

As a class, fluoroquinolones are some of the most commonly used antibiotics worldwide. Their use carries a significant risk of neurotoxicity, for both the peripheral and central nervous system.

Neuropathy After Total Knee Arthroplasty

In a large series of cases from the Mayo Clinic, 54 cases of new neuropathy occurred in 14,450 total knee arthroplasties. Most were isolated peroneal neuropathies. No specific risk factors were identified.

NOACs vs. Warfarin: What Are the Data in Patients With Traumatic Brain Injury and Intracranial Hemorrhage?

A three-year analysis of a prospectively maintained database with traumatic brain injury patients revealed that novel oral anticoagulant use is associated with increased risk of intracranial hemorrhage progression, neurosurgical intervention, and mortality.

Darolutamide Tablets (Nubeqa)

Darolutamide should be prescribed to patients with nonmetastatic, castration-resistant prostate cancer.

Carpal Tunnel Syndrome in the Extreme Elderly

Carpal tunnel syndrome (CTS), when seen in the very elderly, usually is severe and is not reliably diagnosed by ultrasound. Nerve conduction studies and electromyography are the most sensitive and specific tests to make accurate diagnosis of CTS.