Internal Medicine Alert
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Cholesterol Levels and Predicted Survival Rates Among Elderly Women
Researchers found neither low levels of high-density lipoprotein nor high levels of low-density lipoprotein were associated with predicted survival in older women. This finding is consistent with other studies of cholesterol and mortality in the elderly.
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Bempedoic Acid (Nexletol)/Bempedoic Acid and Ezetimibe (Nexlizet)
Bempedoic acid and bempedoic acid/ezetimibe should be prescribed as a supplement to diet and maximally tolerated statin therapy in adults with heterozygous familial hypercholesterolemia or established atherosclerotic cardiovascular disease who need additional LDL-C lowering.
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Heart Rate and Diastolic Blood Pressure in Chronic Aortic Regurgitation Patients
A retrospective observational study of patients with moderate to severe aortic regurgitation showed the independent predictive value of diastolic blood pressure and resting heart rate for all-cause mortality under medical management.
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Using Apple Cider Vinegar for Weight Management on a Restricted Diet
Supplementation with 30 mL of apple cider vinegar combined with a restricted calorie diet may lower body weight, body mass index, and serum triglyceride levels in people with obesity.
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Are Epidural Steroid Injections Cost-Effective?
In a retrospective review of patients treated for low back pain and lumbar radiculopathy at the Cleveland Clinic, at three- and six-month follow-up, epidural steroid injections were no better than conservative therapies in quality of life measures or overall cost of medical care.
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Incidence of Cardiovascular Disease and All-Cause Mortality: Does the Type of Meat Consumed Matter?
Investigators found consuming more processed meat, unprocessed red meat, or poultry (but not fish) was closely connected to a higher risk for incident cardiovascular disease. Meanwhile, consuming processed meat or unprocessed red meat (but neither fish or poultry) was strongly associated with a higher risk of all-cause mortality.
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A ‘Normal’ Initial ECG?
The ECG in the figure was obtained from a 30-year-old man who was admitted to the hospital to “rule out myocardial infarction.” His symptoms of chest discomfort were thought to be atypical and unlikely to be due to a cardiac etiology. His initial ECG (not shown) was interpreted as normal. Evaluation, including serial troponins and stress testing, were deemed normal. Before sending the patient home, the ECG in the figure was obtained.
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Peanut (Arachis hypogaea) Allergen Powder-dnfp (Palforzia)
This is the first FDA-approved oral immunotherapy for desensitizing peanut allergy in children to help reduce the risk of allergic reactions.
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The Safety and Effectiveness of Pyrethroid Insecticides as the Battle Against Mosquitoes Continues
There is a statistical association between a urine test suggestive of exposure to pyrethroid insecticides and increased mortality over the subsequent 14 years.
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Optimal Antithrombic Therapy After PCI for Atrial Fibrillation Patients
In three subgroups of coronary artery disease patients with atrial fibrillation, apixaban plus a P2Y12 inhibitor provided superior safety and similar efficacy outcomes as treatment with warfarin, aspirin, or both for six months.