Internal Medicine Alert
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Inappropriately Broad Empiric Antibiotics, Higher Mortality, and Community-Onset Sepsis
A retrospective cohort study revealed broad-spectrum antibiotics were unnecessarily prescribed to patients with community-onset sepsis and were associated with worse outcomes and higher mortality.
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Insulin Lispro-aabc Injection (Lyumjev)
Lyumjev is indicated to improve glycemic control in adults with diabetes mellitus.
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Clostridioides difficile: Risk Factors for Disease
Approximately one-tenth of asymptomatic patients with Clostridioides difficile colonization went on to develop disease. A wide range of antibiotic exposures represent a significant risk.
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Benefits of Exercise in Established Atrial Fibrillation
A large, long-term, prospective, Norwegian population study of patients with established atrial fibrillation revealed physical activity at or above recommended levels reduces all-cause and cardiovascular mortality vs. atrial fibrillation patients who are inactive.
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Group Beating from Wenckebach?
The two rhythm strips in the figure were recorded just a few minutes apart. There is group beating. Is the rhythm the result of atrioventricular (AV) Wenckebach (second degree AV block, Mobitz Type I)?
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Elagolix, Estradiol, and Norethindrone Acetate Capsules (Oriahnn)
Elagolix-EN should be prescribed to manage heavy menstrual bleeding associated with uterine leiomyomas (fibroids) in premenopausal women.
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MUCH Ado About WUCH
In a long-term, fixed-drug therapy of hypertension study, masked uncontrolled and white coat uncontrolled hypertension exhibited poor reproducibility over four years.
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How Does Weight Loss Affect Lower Urinary Symptoms and Incontinence in Obese and Overweight Women?
Weight loss interventions were associated with improvements in urinary incontinence in overweight and obese women at one to 2.9 years.
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Disability After Minor Stroke and TIA — Secondary Analysis of the POINT Trial
Although the data from this analysis suggest disability might be less with dual antiplatelet therapy, differences between the groups were small, did not show robust findings, and did not reach statistical significance in most of the analyses.
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