Internal Medicine Alert
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What Is the Rhythm? What Is the Culprit Artery?
The ECG in the figure was obtained from a middle-aged man with chest pain. What can one say about the cardiac rhythm? How can one determine the “culprit” artery?
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Viloxazine Extended-Release Capsules (Qelbree)
Viloxazine should be prescribed to treat ADHD in patients age 6 to 17 years.
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Intracranial Plaque Rupture and Stroke
An MRI study of cerebral circulation in patients with embolic stroke of undetermined etiology showed evidence of atherosclerotic plaque in most patients.
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Dasiglucagon Injection (Zegalogue)
Dasiglucagon should be prescribed to treat severe hypoglycemia in pediatric and adult patients (≥ age 6 years).
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Antibiotics: Less Is Better, Sometimes
In England, and likely in many other areas of the world, antibiotics are given for longer than necessary. Excessively long durations of antibiotic use do not help patients and risk leading to more resistant infections.
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Is Empagliflozin Safe in Combination with a Neprilysin Inhibitor for Heart Failure?
A prespecified subgroup analysis of heart failure patients with reduced ejection fraction who were on neprilysin inhibitors before empagliflozin was administered (vs. those not on neprilysin inhibitors) showed the reduction in mortality and hospital admissions for heart failure was not attenuated by concurrent neprilysin use.
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Is Metformin a Wonder Drug?
An analysis of patients taking metformin for diabetes showed they were less likely to report back, knee, neck/shoulder, or multisite musculoskeletal pain.
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What About These T Waves?
The ECG in the figure was obtained from a middle-aged man with new-onset chest pain. How would one interpret this tracing?
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Bamlanivimab and Etesevimab Injection
Bamlanivimab and etesevimab should be prescribed to treat mild-to-moderate COVID-19 in adults and pediatric patients (age 12 years and older, weight at least 40 kg) who test positive for COVID-19 and are at high risk for progressing to severe disease and/or hospitalization.
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Compression Garments Effective in Reducing Cellulitis
Researchers examined the benefit of compression garments in patients with lower extremity edema at risk for cellulitis. Eligible patients reported significant edema for more than three months in one or both legs, and a history of two or more episodes of cellulitis in the same leg within the previous two years.