Internal Medicine Alert
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Do Anti-Inflammatory Drugs Cause More Chronic Pain?
Acute inflammation may protect against the development of chronic pain through neutrophil activation. Using nonsteroidal anti-inflammatory drugs may blunt that response and contribute to chronic pain.
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HPV Vaccination Rate Needs Improvement
The prevalence of HPV infections and their sequelae remain high, although this is a problem that is preventable with available vaccines.
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Anticoagulation Therapy in Octogenarians with Atrial Fibrillation
In patients age 80 years and older with atrial fibrillation who were not considered for oral anticoagulants because of serious comorbidities, one-quarter of the recommended daily dose of edoxaban was superior to placebo for preventing thromboembolic events.
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Sodium Restriction in Chronic, Stable Heart Failure Patients
A study of a low-sodium diet for chronic, stable heart failure patients after one year showed no difference in hard clinical outcomes, but the degree of sodium restriction was modest.
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What Is This Tachycardia?
How would one interpret the tachycardia in the ECG? Is the rhythm ventricular tachycardia or some form of supraventricular tachycardia? How should one proceed?
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Tirzepatide Injection (Mounjaro)
Tirzepatide can be prescribed as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.
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Mortality, Days Alive Outside Institutions Among Older Patients After Tracheostomy
Medicare beneficiaries who underwent tracheostomy and gastrostomy tube placement often remained institutionalized beyond three months, with three-, six-, and 12-month mortality greater than 40%, 50%, and 60%, respectively.
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Did You See Both ECG Findings?
The ECG in the figure was obtained from an older man with new chest pain. There are two principal ECG findings on this tracing. Do you see both?
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Weight Loss and Other Interventions to Alleviate Obstructive Sleep Apnea
Obesity is a primary cause of obstructive sleep apnea (OSA), and improvements in weight and other lifestyle factors can yield benefits for OSA and related comorbidities.
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Daridorexant Tablets (Quviviq)
Daridorexant can be prescribed to adult patients with insomnia characterized by difficulty with sleep onset and/or sleep maintenance.