Internal Medicine Alert
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Determining the ‘Culprit’ Artery
How would one interpret the ECG in the figure, obtained in the ED from a middle-aged man with new chest pain? -
Aducanumab-avwa Injection (Aduhelm)
The FDA has approved a new, but controversial, treatment for Alzheimer’s disease. -
Using Procalcitonin to Limit Antibiotic Treatment for Sepsis Reduces Infection-Related Adverse Events
By shortening the duration of antibiotic therapy, a procalcitonin-guided protocol decreased the rate of infection-associated adverse effects, decreased costs, and reduced mortality in patients with sepsis. -
Pegcetacoplan Injection (Empaveli)
The FDA has approved a new treatment for paroxysmal nocturnal hemoglobinuria, a rare, life-threatening blood disease. -
Stroke and Risk of Suicide
Stroke should be considered a risk factor for suicide. Tactics to screen and treat depression and suicidal ideation should be an important component of long-term follow-up and care for stroke patients. -
Rapid Intermittent Bolus of Hypertonic Saline May Be Better Way to Correct Symptomatic Hyponatremia
Hypertonic saline given via rapid intermittent bolus therapy was as effective and safe as slow continuous infusion, and was associated with a lower rate of recorrecting treatment and higher efficacy in achieving goal sodium within one hour. -
The Danger of ADHD Overdiagnosis
A growing concern about overdiagnosis of attention-deficit/hyperactivity disorder in adolescents and children demonstrates a need for a decisive answer to this concern. -
Importance of Atherosclerotic Disease Risk Factors in Myocardial Infarction Patients
ST-elevation myocardial infarction patients without standard risk factors recorded a higher all-cause mortality rate that was particularly evident in women. Using proper therapy in these patients may attenuate this risk. -
Antibiotic Therapy: How Long Is Long Enough?
The CDC and the American College of Physicians have provided advice on the best practice regarding the duration of antibiotic therapy for several common infections. -
Giving the Cold Shoulder to Drug Therapy for Atrial Fibrillation
In two randomized trials published simultaneously, cryoballoon ablation proved superior to drug therapy for prevention of arrhythmia recurrence in patients with paroxysmal atrial fibrillation.