Internal Medicine Alert
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Baricitinib Tablets (Olumiant)
Baricitinib is the first FDA-approved systemic treatment of alopecia areata.
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Outcomes of COVID-19-Associated Acute Myocarditis
In a review of COVID-19-associated acute myocarditis, investigators learned it is a rare complication that can occur without concomitant pneumonia, and frequently presents as cardiogenic shock. With supportive therapy, the short-term mortality rate is low.
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Comparing CT Angiography to Invasive Angiography for Stable Chest Pain Patients
A trial of initial coronary CT angiography vs. invasive angiography revealed outcomes over a median 3.5-year follow-up were similar, but procedure-related complications were more common in the invasive group.
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Is the Canadian Syncope Risk Score Valid?
Researchers found the Canadian Syncope Risk Score accurately predicts which patients are low risk for discharge. However, since it is driven largely by the physician’s final risk classification at ED discharge, the score’s clinical utility is uncertain.
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Smoking Cessation After Atrial Fibrillation Diagnosis Could Lower Dementia Risk
A cohort study of patients with atrial fibrillation (AF) in South Korea revealed patients who stopped smoking after AF diagnosis were at lower risk for developing dementia than those who continued smoking.
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Tapinarof Cream 1% (Vtama)
Tapinarof can be prescribed to treat plaque psoriasis in adults.
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Intensive Blood Pressure Control May Augment Cerebral Blood Flow
Patients with hypertension were randomized to intensive vs. standard blood pressure control and underwent baseline and follow-up cerebral perfusion imaging. Intensive blood pressure treatment was associated with improved cerebral perfusion over time.
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COVID-19 Pre-Exposure Prophylaxis
The combination of tixagevimab and cilgavimab (Evusheld) was demonstrated to be effective in the prevention of symptomatic COVID-19, but much remains to be learned as SARS-CoV-2 continues to evolve.
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Who Can Receive the Non-mRNA COVID-19 Vaccine Now?
The FDA recently limited the use of the Janssen COVID-19 vaccine.
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Physical Activity and Diet of U.S. Adults Following Bariatric Surgery
Patients who underwent bariatric surgery reported more physical activity and less energy intake than those who were eligible for, but did not undergo, bariatric surgery; however, physical activity still did not reach recommended levels.