Internal Medicine Alert
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Intensive Blood Pressure Control May Augment Cerebral Blood Flow
Patients with hypertension were randomized to intensive vs. standard blood pressure control and underwent baseline and follow-up cerebral perfusion imaging. Intensive blood pressure treatment was associated with improved cerebral perfusion over time.
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COVID-19 Pre-Exposure Prophylaxis
The combination of tixagevimab and cilgavimab (Evusheld) was demonstrated to be effective in the prevention of symptomatic COVID-19, but much remains to be learned as SARS-CoV-2 continues to evolve.
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Who Can Receive the Non-mRNA COVID-19 Vaccine Now?
The FDA recently limited the use of the Janssen COVID-19 vaccine.
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Physical Activity and Diet of U.S. Adults Following Bariatric Surgery
Patients who underwent bariatric surgery reported more physical activity and less energy intake than those who were eligible for, but did not undergo, bariatric surgery; however, physical activity still did not reach recommended levels.
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Do Anti-Inflammatory Drugs Cause More Chronic Pain?
Acute inflammation may protect against the development of chronic pain through neutrophil activation. Using nonsteroidal anti-inflammatory drugs may blunt that response and contribute to chronic pain.
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HPV Vaccination Rate Needs Improvement
The prevalence of HPV infections and their sequelae remain high, although this is a problem that is preventable with available vaccines.
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Anticoagulation Therapy in Octogenarians with Atrial Fibrillation
In patients age 80 years and older with atrial fibrillation who were not considered for oral anticoagulants because of serious comorbidities, one-quarter of the recommended daily dose of edoxaban was superior to placebo for preventing thromboembolic events.
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Sodium Restriction in Chronic, Stable Heart Failure Patients
A study of a low-sodium diet for chronic, stable heart failure patients after one year showed no difference in hard clinical outcomes, but the degree of sodium restriction was modest.
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What Is This Tachycardia?
How would one interpret the tachycardia in the ECG? Is the rhythm ventricular tachycardia or some form of supraventricular tachycardia? How should one proceed?
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Tirzepatide Injection (Mounjaro)
Tirzepatide can be prescribed as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.