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Internal Medicine Alert

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Articles

  • ECG Review: Right Answer/Wrong Reason

    The ECG shown in the Figure was obtained in the emergency department (ED) from a 61-year-old woman with a history of significant hypertension. She was alert, oriented, and not in acute distress at the time this tracing was recorded, although she was markedly hypertensive and experiencing some chest pain. No prior ECG was available. The patient was treated in the ED with several doses of Adenosine and eventually converted to sinus rhythm. Your thoughts on the rhythm and the management?
  • Pharmacology Update: Amlodipine/Atorvastatin Tablets

    The FDA has approved a combination product of amlodipine and atrovastatin for the treatment of patients with comorbid hypertension and hypercholesterolemia.
  • A Prospective Study of Aspirin Use and the Risk for Colorectal Adenoma

    Although regular aspirin use reduces the risk for colorectal adenoma formation as shown in previous randomized-controlled trials, the protective effect now seems to be greatest at substantially higher doses (> 14 standard tablets/week) than currently recommended for cardiovascular prophylaxis.
  • When Should I Order a BNP?

    B-type natriuretic peptide (BNP) is a biomarker released by cardiac ventricular myocytes. Its usefulness is mainly in the emergency room for the evaluation of acute dyspnea, to evaluate for cardiac failure. BNP may have usefulness as a screening test for preclinical heart disease, for risk stratification and for guidance with therapy.
  • Clinical Briefs

    Exemestane after Tamoxifen Therapy in Breast Cancer; An Analysis of How Long Patients Remain on Various BP Therapies; Endothelial Dysfunction with Insulin Resistance and CWT in Hypertension
  • This Rule Doesn’t Rule

    A clinical prediction rule helps identify patients with knee pain who might benefit from orthopedic surgery.
  • Diets’ Clout with Gout

    Diets low in red meat and fish and high in vegetables and low-fat dairy products are associated with a decrease in the incidence of gout.
  • Clinical Briefs

    This meta-analysis reviewed trials of antioxidants for prevention of GI cancer.
  • Pharmacology Update: Omega-3-Acid Ethyl Esters Capsules (Omacor)

    The FDA has approved a new lipid regulating agentthe ethyl esters of omega-3 fatty acids for the treatment of high triglyceride levels.
  • Beware of Using Fibrates with Statins

    Combining a fibrate with a statin increases the risk of rhabdomyolysis by more than 10 times the use of a statin alone.