Internal Medicine Alert
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It’s Not All About the Cough
Be careful about relying on clinical queries that focus on the presence of cough for two or more weeks, which could lead to delays in the diagnosis of nearly half of pulmonary tuberculosis cases.
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Is Routine Stress Testing After Coronary Revascularization Necessary?
A multicentered study of routine stress testing at one year post-percutaneous coronary revascularization compared to usual care in patients with at least one high-risk coronary anatomic or clinical feature failed to show improved clinical outcomes at two years follow-up.
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Apixaban for Venous Thromboembolism in Patients with End-Stage Kidney Disease
There is a lower risk of bleeding for those taking apixaban during venous thromboembolism treatment compared to warfarin in patients with end-stage kidney disease.
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Patients with Chronic Pain and Opioid Misuse: What Treatment Works?
Among primary care patients diagnosed with comorbid chronic pain and opioid misuse, researchers found a specially designed, mindfulness-based group therapy showed superiority to generic supportive group therapy in reducing opioid use and controlling symptoms of chronic pain.
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The Clue in Lead II
How should one interpret the ECG in the figure? The figure was obtained from a 40-year-old man who was hemodynamically stable at the time this tracing was recorded. The key clue is in lead II.
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Ruxolitinib Cream (Opzelura)
Ruxolitinib cream can be prescribed to treat nonsegmental (bilateral) vitiligo in adult and pediatric patients age 12 years and older.
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Periodontal Disease as an Independent Risk Factor for Cardiovascular Disease
Researchers used data from the 2013 to 2014 period of the National Health and Nutrition Examination Survey to study possible connections between poor oral health and the likelihood of developing cardiovascular disease.
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Is Illicit Substances Use Associated with Atrial Fibrillation?
An observational study of a huge cohort of patients admitted to California hospitals showed patients who used cocaine, methamphetamine, opiates, and cannabis were at a higher risk of developing atrial fibrillation vs. those with similar risk factors who did not use the substances.
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The Right Dose at the Right Time: Improving Hypertension Outcomes
An online study of evening vs. morning administration of patients’ usual antihypertensive medications, with a median five-year follow-up, revealed there is no difference in major cardiovascular outcomes between the two periods.
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Is Long-Term Antidepressant Use Hurting Patients?
Long-term antidepressant use could lead to elevated risks of coronary heart disease, along with higher cardiovascular disease mortality and all-cause mortality rates.