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Internal Medicine Alert

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  • The Outpatient Bleeding Risk Index

    In 1998, Beyth and colleagues developed a modified outpatient bleeding risk index. In this prospective study conducted at the University of Ottawa, 222 patients with diagnosed pulmonary embolism or deep venous thrombosis were observed for an average of 18.5 months.
  • More Bad News for Folic Acid

    Elevated homocysteine levels have been associated with atherosclerosis. Folic acid supplementation is a simple, inexpensive way to reduce homocysteine levels, which has become popular for secondary prevention in patients with coronary artery disease (CAD), despite a paucity of long-term clinical trial data. Thus, Liem and colleagues studied 593 patients with stable CAD on statins who were randomized to open-label folic acid 0.5 mg/d or standard care, which included aggressive pursuit of lipid goals.
  • Pharmacology Watch

    FDA Advisory Committee recommends approval of dabigatran, safety of proton pump inhibitors, effectiveness of glucosamine and chondroitin, FDA Actions.
  • Black and White Differences in Hemoglobin A1c Levels

    American non-Hispanic black persons had higher HbA1c levels than white persons at all levels of glycemia, and this difference increased as glucose intolerance worsened.
  • Clinical Briefs By Louis Kuritzky, MD

    Since the publication of the allhat trial, clinicians have progressively relied upon diuretic-based regimens to manage hypertension (HTN).
  • Should Everyone Be on Fish Oils?

    Marine n-3 PUFAs act as pleiotropic agents on the cardiovascular system with a diverse range of effects most of which are beneficial for patients with known cardiovascular disease and possibly, they may even have beneficial effects with regard to the primary prevention of cardiovascular disease.
  • Lifetime Follow-up Care after Childhood Cancer

    Lifetime surveillance is required after successful treatment of childhood cancers, since up to 75% of survivors develop serious complications and other late effects.
  • Dabigatran Etexilate mesylate Capsules (Pradaxa®)

    Dabigatran is indicated for reducing the risk of stroke and systemic embolism in patients with non-valvular atrial fibrillation.
  • Is It a Coincidence that Death Rhymes with Breath?

    Pulmonary function can help predict cardiovascular death risk in individuals in the intermediate-risk group of Framingham Risk Scores.
  • ECG Review: P Pulmonale?

    The ECG above was obtained from a slender and previously healthy 27-year-old woman having atypical chest discomfort. Is there evidence of chamber enlargement?