Internal Medicine Alert
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Doxycycline Plus a Beta-Lactam to Treat Inpatients with Community-Acquired Pneumonia
In this retrospective study of an elderly male population hospitalized with community-acquired pneumonia, the combination of doxycycline with a beta-lactam was at least as effective as a respiratory fluoroquinolone or a combination of a beta-lactam with azithromycin.
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The Great Imitator Imitates Again
This case report serves as a reminder that even though pancolitis from secondary syphilis is rare, syphilitic proctitis is a not-uncommon manifestation of syphilis — and that syphilis can present as almost anything — even long COVID.
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Benefits, Risks of Dual Antiplatelet Therapy After Acute Ischemic Stroke or TIA
It will be important to determine the actual frequency of the CYP2C19 loss-of-function gene. Clinicians should consider point-of-care testing for patients before selecting and initiating dual antiplatelet therapy.
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Long-Term Outcomes in Intracerebral, Intraventricular Hemorrhage
It is important to avoid giving a poor prognosis early in the clinical course, and to continue supportive care until the long-term outcome truly is understood.
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The Dental Procedure-Infective Endocarditis Link Controversy Continues
Infective endocarditis was more common with dental surgery or tooth extractions in the preceding four weeks in high-risk patients. Researchers abrogated this risk with antibiotic prophylaxis before the procedure.
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Sodium Phenylbutyrate and Taurursodiol for Oral Suspension (Relyvrio)
Relyvrio can be prescribed to treat amyotrophic lateral sclerosis in adults.
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CDC Tries Less Rigid Approach to Opioid Prescribing Guidelines
Agency underscores voluntary nature of its recommendations, highlights new science and collaboration that went into the revisions.
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Advocates Underscore Importance of Colonoscopies
Follow-up media reports about possibly incomplete research on this subject may have created confusion.
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Hot Trials from the European Society of Cardiology Annual Congress
Some highlights from two key studies presented in Barcelona, Spain, between Aug. 26 and Aug. 29, 2022, along with Dr. Crawford’s personal commentary on both.
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Family Members of Critically Ill Patients with SARS-CoV-2 Pneumonia Have a High Burden of Symptoms of PTSD
This multicenter cohort study found a high incidence of post-traumatic stress disorder symptoms among family members of COVID-19 patients at three months after the index intensive care unit admission.