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A randomized, diet-controlled interventional study demonstrates that moderate alcohol consumption reduces plasma C-reactive protein and fibrinogen levels.
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Alefacept is a new biological agent for the treatment of moderate-to-severe plaque psoriasis. The drug, which targets T lymphocytes, is a fusion protein combining the binding site of lymphocyte function-associated antigen-3 and the Fc portion of human IgG1.
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Women who habitually sleep 5 or fewer or 9 or more hours per night have an increased risk of coronary heart disease compared with those who sleep 7 or 8 hours a night.
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Smallpox Vaccination Guidelines Published by CDC; Nurses: Delay
Vaccination Program; Viagra Effective for Depression Treatment;
Finisteride/Doxazosin no Better than Placebo for Urinary Obstruction;
Serevent Receives Dear Doctor Letter
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Clinical Scenario: The ECG in the Figure shows normal sinus rhythm at a rate of 80 beats/minute. The PR, QRS, and QT intervals are normal. There is an rSR pattern in lead III. The axis is +40°. There is no sign of chamber enlargement. The most remarkable finding on this tracing is the presence of subtle but real ST segment elevation in multiple leads including I, II, aVF, and V2 through V6.
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Syncope, Driving Recommendations, and Clinical Reality: Survey of Patients; Combination Treatment of Angiotensin-II Receptor Blocker and Angiotensin-Converting-Enzyme Inhibitor in Non-Diabetic Renal Disease (COOPERATE): A Randomized Controlled Trial; Early Onset of Action and Efficacy of a Combination of Calcipotriene and Betamethasone Dipropionate in the Treatment of Psoriasis
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Elevated CRP levels are associated with inducible ischemia in patients with stable coronary disease, particularly among those not treated with beta-blockers or statins.
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Treatment with natalizumab, an antibody to a4 integrin, led to fewer inflammatory brain lesions and fewer relapses in patients with relapsing multiple sclerosis.
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Current guidelines for NSAID use in patients at high risk for ulcer disease recommend use of NSAIDs selective for cyclo-oxygenase-2 inhibition or nonselective NSAIDs plus a proton pump inhibitor. This study compared diclofenac plus omeprazole with celecoxib in patients with previous GI hemorrhage. Neither regimen successfully prevented rebleeding, and both exhibited significant toxicities.
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Screening for lung cancer with helical CT has high costs and uncertain benefits.
