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Articles

  • Low-Dose Aspirin in the Primary Prevention of Cancer

    By Barbara A. Phillips, MD, MSPH Professor of Medicine, University of Kentucky; Director, Sleep Disorders Center, Samaritan Hospital, Lexington, KY Dr. Phillips serves on the speakers bureau of Cephalon, Boehringer Ingelheim, Merck, ResMed, and GlaxoSmithKline and is a consultant for Boehringer Ingelheim, Wyeth-Ayerst, and ResMed. Synopsis: There was no overall effect of 100 mg aspirin every other day on total cancer among nearly 40,000 women randomized to aspirin or placebo and followed for an average of 10 years.
  • Pharmacology Update Ibandronate Sodium Tablets (BonivaTM)

    By William T. Elliott, MD, FACP, and James Chan, PharmD, PhD Dr. Elliott is Chair, Formulary Committee, Northern California Kaiser Permanente; Asst. Clinical Professor of Medicine, University of California, San Francisco; Dr. Chan is Pharmacy Quality and Outcomes Manager, Kaiser Permanente, Oakland, CA Drs. Chan and Elliott report no financial relationships to this field of study.
  • Rifaximin to Control Travelers’ Diarrhea

    By Malcolm Robinson, MD, FACP, FACG Emeritus Clinical Professor of Medicine, University of Oklahoma College of Medicine, Oklahoma City, OK Disclosure; Dr. Robinson serves as a consultant for TAP, Pfizer, Janssen, Eisai, J&J-Merck, and Procter & Gamble, is on the speakers bureau of Janssen, Eli Lilly, Solvay, TAP, and Aventis, and does research for Forest Labs, Wyeth-Ayerst, AstraZeneca,and Centocor. Synopsis: Rifaximin, a newly released nonabsorbed antibiotic, appears to safely and effectively prevent the onset and substantial morbidity of travelers diarrhea.
  • Cardiac Resynchronization Therapy in CHF Who and When

    By Harold L. Karpman, MD Clinical Professor of Medicine, UCLA School of Medicine Disclosure; Dr. Karpman reports no financial conflicts of interest in this field of study. Despite the recent explosion of pharmacologic agents available for the treatment of congestive heart failure (CHF), many patients continue to be severely symptomatic and their prognosis remains poor.
  • Fluid Balance in Runners: Getting it Right

    By Joseph E. Scherger, MD, MPH Clinical Professor, University of California, San Diego Disclosure; Dr. Scherger reports no financial conflicts to this field of study.
  • Does Stress Management Improve Markers of Cardiovascular Disease?

    By Ralph R. Hall, MD, FACP Emeritus Professor of Medicine, University of Missouri, Kansas City School of Medicine Disclosure; Dr. Hall is a consultant for Sanofi-Aventis. Synopsis: Exercise and stress management improved markers of cardiovascular disease more than usual care alone.
  • Clinical Briefs By Louis Kuritzky, MD

    White-Coat HTN Make Diabetics Walk Treatment of Complicated Grief
  • Vitamin E, Donepezil and MCI

    By Norman R. Relkin, MD, PhD Associate Professor of Clinical Neurology and Neuroscience at New York Presbyterian Hospital-Cornell Campus. Dr. Relkin is on the speaker's bureau of Pfizer, Eisai, and Athena Diagnostics and does research for Pfizer and Merck.
  • Rifamixin for the Prevention of Traveler’s Diarrhea?

    Rifamixin, a nonabsorbed oral antibiotic, is effective for preventing traveler's diarrhea, according to new research.
  • Pramlintide Acetate Injection (Symlin)

    By William T. Elliott, MD, FACP, and James Chan, PharmD, PhD Dr. Elliott is Chair, Formulary Committee, Northern California Kaiser Permanente; Associate Clinical Professor of Medicine, University of California, San Francisco; Dr. Chan is Pharmacy Quality and Outcomes Manager, Kaiser Permanente, Oakland, CA. Drs. Chan and Elliott report no financial relationships to this field of study. A synthetic analog of human amylin has been approved for the treatment of type 1 and type 2 diabetics. Pramlintide is a 37-amino acid peptide which differs from human amylin with substitution of three amino acids at positions 25, 28, and 29. It represents the first of a new class of amylinomimetic antidiabetic compounds. It is marketed by Amylin Pharmaceuticals, Inc as Symlin.