Internal Medicine Alert
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Pharmacology Update: Insulin Detemir Injection (Levemir®)
The FDA has approved a new long-acting insulin analog produced by DNA technology. -
Breast Cancer in Young Women: The M.D. Anderson Experience
Breast cancer in young women is uncommon, but when it does occur, it is thought to be very aggressive. In this large series of young (< 35 years old) patients from a single institution seen over a 13-year period, high tumor grade, hormone receptor negativity, and family history of ovarian cancer turned out to be significant negative prognostic indicators. -
A New Treatment for Diabetes?
Patients who had both diabetes and sleep apnea had improved HbA1c and postprandial glucose when they used Continuous Positive Airway Pressure (CPAP) for more than 4 hours a night. -
Pharmacology Watch: Antibiotic Treatment of Acute Lower Respiratory Infection
A new study from England defines acute lower respiratory tract infection as an uncomplicated acute illness, with cough as the primary symptom and at least one symptom or sign localized to the lower respiratory tract including sputum, chest pain, dyspnea, or wheeze. -
Treatment Alternatives for Chronic Hepatitis B Virus Infection: A Cost-Effectiveness Analysis
By Malcolm Robinson, MD, FACP, FACG Emeritus Clinical Professor of Medicine, University of Oklahoma College of Medicine, Oklahoma City, OK Dr. Robinson serves as a consultant for TAP, Pfizer, Janssen, Eisai, J&J-Merck, and Procter & Gamble, is on the speakers bureau of Janssen, Eli Lilly, Solvay, TAP, and Aventis, and does research for Forest Labs, Wyeth-Ayerst, AstraZeneca, and Centocor. -
Treatment of Tuberculosis and Latent Tuberculosis Infection
The treatment of pulmonary tuberculosis is divided into an initial phase of four drugs for two months.
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Pharmacology Update Medroxyprogesterone Acetate Injection (depo-subQ provera 104)
By William T. Elliott, MD, FACP, and James Chan, PhD, PharmD Dr. Elliott is Chair, Formulary Committee, Northern California Kaiser Permanente; Associate Clinical Professor of Medicine, University of California, San Francisco; Dr. Chan is Pharmacy Quality and Outcomes Manager, Kaiser Permanente, Oakland, CA. Drs. Chan and Elliott report no financial relationships to this field of study. -
Autonomic Peripheral Neuropathy
By Norm Latov, MD Professor of Neurology and Neuroscience and Director of the Peripheral Neuropathy Center at Weill Medical College at Cornell University. Dr. Latov is a consultant for Quest Diagnostics and Talecris Inc., is a stockholder of Therapath LLC, and has royalties in Athena Diagnostics. Synopsis: The availability of sensitive and reproducible measures of autonomic function has improved physicians ability to diagnose these disorders. -
Etiology of Elevated Troponin Levels Other Than in Acute Coronary Syndromes
By Harold L. Karpman, MD Clinical Professor of Medicine, UCLA School of Medicine Dr. Karpman reports no financial relationship to this field of study. -
Clinical Briefs
Vitamin E and Donepezil for the Treatment of Mild Cognitive Impairment Foot Small Muscle Atrophy Before the Detection of Clinical Neuropathy Statins and the Risk of Colorectal Cancer