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Available statins are associated with a small increased risk of hepatotoxicity, but not muscle toxicity or drug discontinuation for adverse effects.
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Panitumumab is a human monoclonal antibody that is approved for the treatment of colorectal carcinoma.
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Stroke remains the third lead ing cause of death in America. Risk of stroke after TIA is greatly magnified, such that as many as 20% will suffer a stroke within 90 days.
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Aggressive statin therapy is associated with slowed progression and even regression of atherosclerosis.
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Until now, there has been no proven therapy for nonalcoholic steatohepatitis. Pioglitazone, known to improve insulin resistance, was shown to result in metabolic and histologic improvement in this common and potentially highly morbid malady.
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When compared to physiotherapy and watchful waiting, corticosteroid injection in the treatment of lateral epicondylitis helps in the short term, but had the worst results at one year.
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The FDA has approved an estradiol gel for the management of hot flashes associated with menopause.
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Elevated levels of brain natriuretic peptide (BNP) reflect cardiac ventricular wall stress, and correlate well with the presence and severity of heart failure.
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With the exception of prescription of ACE inhibitors or blockers, performance measures for heart failure do not predict mortality or rehospitalization in the first 60 to 90 days after discharge.
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In the setting of screening colonoscopy, longer durations of observation during withdrawal of the colonoscope were associated with higher detection rates for neoplasia.
