Silverman and colleagues used the emergency departments in 8 hospitals to assess the role of MgSO4 in acute asthma in a sizeable number of patients (n = 248).
A new aldosterone receptor antagonist has been approved by the FDA. Eplereone, a selective aldosterone receptor antagonist, is the first approval in this class since the introduction of spironolactone close to 3 decades earlier.
Daily vitamin E and multivitamin-mineral supplementation and acute RTI in elderly persons; B-Type natriuretic peptide levels and outcome in patients with heart failure; influence of companions during primary care medical encounters
This cohort study prospectively compared the rate of change in the amount of coronary calcification before and after lipid-lowering therapy with the cholesterol synthesis enzyme inhibitor cerivastatin.
There appears to be an increase in ovarian cancer with long-term estrogen-only hormone replacement therapy.
Ambulatory blood pressure monitoring is a useful adjunct for evaluating white coat hypertension, but little is known about its effect on BP. Thus, Hermida and associates from Spain studied 538 patients with mild-to-moderate office hypertension using ABPM for 48 hours.
There is evidence that diet could play a role in Alzheimer's disease (AD) risk. This epidemiologic study examined the risk of AD between quartiles of calorie, carbohydrate, fat, and protein intake after adjusting for confounders.
In patients with heart failure and diabetes, metformin is not associated with harm and may reduce all cause mortality.
The FDA has approved a new drug for the treatment of advanced breast cancer.
Asymptomatic brain MRI findings of infarct, cerebral aneurysms and benign tumors were fairly common in the general population. The clinical significance of these findings is unknown.
