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The recent indication in an article by Nissen, et al (N Engl J Med. 2007;356:2457-2471) that rosiglitazone (ROSI) might actually increase cardiovascular (CV) risk was met with surprise and dismay by many clinicians and their patients alike.
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The FDA has approved the first mTOR inhibitor for the treatment of advance renal cancer. Temsirolimus is a more water soluble ester of sirolimus and the latter is the principal active metabolite.
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Application of vitamin A to naturally aged skin reduced fine wrinkling
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Patients with early breast cancer did not have fewer recurrences of cancer or improved mortality after eating a diet rich in vegetables and fruit and low in fat.
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Compared to patients over the age of 65 years who were receiving 10 mg of atorvastatin daily, the elderly patients who received 80 mg daily experienced significantly reduced major cardiovascular and coronary events ...
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The ECG in the Figure was obtained from a 59-year old man with hypertension. He was admitted to the hospital to rule out acute infarction because of an "unpleasant sensation" in his chest.
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SSRIs are associated with a low rate of birth defects according to 2 new studies in the New England Journal of Medicine. SSRIs are often taken by women in their childbearing years, but the risk of birth defects has been unclear.
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A prodrug of dextroamphetamine has been approved by the FDA for the treatment of attention-deficit/hyperactivity disorder (ADHD). Lisdexamfetamine is the d-amphetamine covalently bound to l-lysine. It is marketed by Shire US Inc as Vyvanse.
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In patients with suspected pulmonary tuberculosis who are unable to expectorate sputum, culture of 3 induced sputum samples, all collected on the same day, is an effective and efficient means of diagnosis.
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Use of a symptom-driven dose of a combined steroid and albuterol inhaler was equally effective for mild persistent asthma compared to a twice daily steroid inhaler, and resulted in a smaller cumulative dose of inhaled steroids in the six month study period.