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The hope trial convinced many experts that midlife adults (age ≥ 55 years) with existing vasculopathy (history of CAD, CVD, diabetes and CV risk factors) will have improved outcomes on an ACE inhibitor (ramipril, to be specific).
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Although health care providers have a major influence on their patients when they decide to undergo screening for prostate cancer, shared decision making often does not occur despite recommendations.
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Low levels of serum 25-hydroxyvitamin D [25(OH)D] in non-institutionalized older adults were associated with future increased mortality from all causes and from cardiovascular disease.
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Cholinesterase inhibitors place patients at risk for syncope, bradycardia, permanent pacemaker insertion, and hip fracture.
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The antiplatelet effect of clopidogrel is dependent upon its conversion and activation through the 2C19 pathway of the P450 system. Blockade of this pathway occurs because of genetics, in persons who do not have sufficiently active 2C19, and pharmacotherapies that specifically block 2C19. Proton pump inhibitors (PPIs), particularly omeprazole, are recognized to be 2C19 inhibitors. Is there reason for concern?
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The ECG shown above was obtained from a 72-year-old woman as a baseline. How would you interpret her ECG? How many blocked and early findings can you identify?
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The FDA has approved the first treatment for relapsed or refractory peripheral T-cell lymphoma. Pralatrexate, an inhibitor of dihydrofolate reductase, was granted accelerated approval by the FDA. It will be marketed by Allos Therapeutics as Folotyn™.
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Sex hormone-binding globulin (SHBG) is a protein that might seem to be most interesting to the endocrinologist, since its sole function - until very recently - has been thought to be regulation of the availability of gonadal steroids.
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Hand hygiene and facemasks used within 36 hours of patient symptom onset resulted in a small reduction of household transmission of influenza, but adherence to recommended practices was poor despite home-based education.
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One-third of adults older than age 40 has vestibular dysfunction.
