Internal Medicine Alert
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Clinical Briefs
In this issue: Carbon monoxide toxicity in the elderly; Does hypovitaminosis D increase risk of atrial fibrillation in hypertensive patients?; and reflections on the consequences of morning BP surge.
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Liraglutide Injection (Saxenda®)
The glucagon-like peptide (GLP-1) receptor agonist, liraglutide is now approved for weight management in adults.
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Inpatient and Outpatient Care Providers: Why Can’t We Just Work Together?
The authors of this paper did a qualitative study to analyze the barriers and solutions to care coordination between hospitalists and primary care providers in North Carolina.
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Efficacy of Folic Acid Therapy in Primary Prevention of Stroke
Among adults with hypertension in China without a history of stroke or myocardial infarction, the combined use of enalapril and folic acid, compared with enalapril alone, significantly reduced the risk of first stroke.
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Clinical Briefs
This article covers the following topics: the saga of homocysteine and vasculopathy; roflumilast for acute exacerbations in COPD; and treatment of OSA reduces risk of repeat revascularization after PCI.
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Ivabradine Tablets (Corlanor ®)
Ivabradine's effect in reducing heart rate, by acting on the SA node, was most prominent at a higher heart rate, thus minimizing the risk of bradycardia.
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Clindamycin vs. Trimethoprim-Sulfamethoxazole for Uncomplicated Skin Infections
Cure rates did not differ between the treatments and rates of adverse events were similar in the two groups.
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Utility of the New Cholesterol Guidelines
The risk:benefit ratio is much better for moderate- than high-intensity statins.
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Risk of NSAID Use in Patients Receiving Antithrombotic Therapy After Myocardial Infarction
The use of NSAIDs was associated with increased risk of bleeding and excess thrombotic events, even after short-term treatment.
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Wide Tachycardia in a Patient with Chest Pain
The 12-lead ECG and accompanying long lead II rhythm strip in the Figure was obtained from a 70-year-old woman with chest pain. She was hemodynamically stable at the time this ECG was recorded. What is the rhythm?