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Tedizolid Phosphate Injection and Tablets (Sivextro®)

A new oxazolidinone-class antibacterial has been approved for the treatment of acute bacterial skin and skin structure infections.

Prevalence of Rest Tremor in Essential Tremor

Rest tremor is seen in patients with more advanced essential tremor, yet its prevalence varies significantly between patient groups.

Is It Time to Purge Full-Strength Aspirin from the Outpatient Armamentarium?

The current study provides further evidence of a lack of benefit to high-dose maintenance aspirin, along with a suggestion of harm.

Comparative Efficacy and Safety of Blood Pressure-lowering Agents in Adults with Diabetes and Kidney Disease

Although no blood pressure-lowering strategy prolonged survival in adults with diabetes and kidney disease in this meta-analysis, angiotensin-converting enzyme and angiotensin-receptor blockers, alone or in combination, were the most effective pharmacological strategies to prevent the development of end-stage renal disease.

Clinical Briefs

Updates on treatment of depression, the prevention and treatment of osteoporosis, and subclinical thyroid dysfunction as it relates to fracture risk.

Pharmacology Update: Memantine HCl and Donepezil HCl Capsules (Namzaric™)

The addition of memantine to a stable dose of an acetylcholinesterase inhibitor may improve cognitive performance.

PCSK9: A Major New Advance in Cholesterol-lowering Therapy

When added to statin therapy at the maximum tolerated dose, the PCSK9 inhibitor alirocumab reduced low-density lipoprotein cholesterol levels by 62% and also reduced the rate of occurrence of cardiovascular events.

Obesity Paradox and Diabetes

In a prospective cohort study of overweight or obese type 2 diabetics, being overweight was associated with a lower mortality risk, but being obese was not.