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Too Much of a Good Thing
In the United States in 2010 and 2011, an estimated 30% of outpatient oral antibiotic prescriptions may have been inappropriate, a finding that supports the need for establishing a goal for outpatient antibiotic stewardship.
ECG Review: SVT in a 13-Year-Old Patient
The ECG in the figure below was obtained from an otherwise healthy 13-year-old boy. He was alert and hemodynamically stable at the time this ECG was recorded. How should one interpret this tracing?
Clinical Briefs
In this section: comparing blood pressure monitoring techniques; DPP4 agents and heart failure; identifying at-risk groups for hypoglycemia.
Infliximab-dyyb for Injection (Inflectra)
Infliximab-dyyb offers another, possibly less expensive, option for treatment of a number of autoimmune conditions.
Early Chest CT Can Improve Treatment for Community-acquired Pneumonia
In patients with suspected community-acquired pneumonia, early chest CT significantly changed management decisions.
Trimethoprim-sulfamethoxazole vs. Placebo for Skin Abscesses After Incision and Drainage
A multicenter, double-blind, randomized, clinical trial found that a seven-day course of trimethoprim-sulfamethoxazole following incision and drainage (I&D) resulted in a higher rate of cure for skin abscesses compared to I&D and placebo.
Association of Seafood Consumption and Brain Mercury Levels with Brain Neuropathology
Although moderate seafood consumption was correlated with higher brain levels of mercury, these levels were not correlated with brain neuropathology.
Clinical Briefs
In this section: examining autoimmune disorders associated with vitiligo; moderate alcohol consumption is not associated with reduced all-cause mortality; and rethinking the American diet.
Ixekizumab Injection (Taltz)
Ixekizumab is indicated for the treatment of adults with moderate-to-severe plaque psoriasis who are candidates for systemic therapy or phototherapy.
Outcome of PCSK9 Inhibitor-treated Patients
In a meta-analysis of 17 studies, proprotein convertase subtilisin-kexin type 9 serine protease inhibitors markedly reduced low-density lipoprotein cholesterol levels and all-cause mortality, but was associated with a significant increase in neurocognitive adverse events.