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In response to several high-profile drug misadventures including the rofecoxib (Vioxx®) withdrawal from the market, the FDA's Center for Drug Evaluation and Research (CDER) asked the Institute of Medicine (IOM) to assess the drug safety system in the United States.
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Influenza can lead to death from pneumonia as well as exacerbations of underlying diseases of the heart, lungs, or other organ systems. More than 90% of deaths attributed to influenza and pneumonia occur in the elderly, and in the United States the mortality rate has been rising.
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Wait and see prescriptions (WASP) is a new concept for the treatment of otitis media in children.
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Impaired Fasting Glucose (IFG) and impaired glucose tolerance (IGT) appear to be the steps directly preceding the development of overt diabetes.
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A new agent has been approved for the treatment of the neovascular (wet) form of age-related macular degeneration (AMD).
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In this Phase III drug trial, use of a testosterone patch increased desire and the frequency of satisfying sexual activity in naturally menopausal women with hypoactive sexual desire disorder.
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Acetaminophen, taken at the maximum recommended dose for 14 days by healthy adults, can elevate liver enzymes far above the upper limit of normal.
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The FDA has approved the first of a new class of drugs for the treatment of type 2 diabetes. Sitagliptin is a dipeptidyl peptidase-IV (DPP-4) inhibitor.
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After prostatectomy, many men lose erectile function. It has been recently noted that penile stimulation that actively produces cavernosal dilation may reduce the likelihood of loss of function.