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In a large, randomized, controlled trial, screening for prostate cancer did not have a significant effect on mortality from prostate cancer after 20 years of follow-up.
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The use of low-dose aspirin is associated with an almost two-fold increase in the risk of upper gastrointestinal bleeding compared with nonuse and this risk is further increased when low-dose aspirin is combined with clopidogrel, oral anticoagulants, nonsteroidal anti-inflammatory drugs, or high-dose oral corticosteroids.
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A tyrosine kinase inhibitor has been approved for the treatment of medullary thyroid cancer (MTC).
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Anticholinergic drugs for COPD; pioglitazone for diabetes prevention; insulin degludec in Phase 3 trials; and FDA Actions.
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Plasma concentrations of 25-hydroxyvita-min D [25(OH)D] decrease after an inflammatory insult such as knee surgery and, therefore, are unlikely to be a reliable measure of 25(OH)D status in patients with evidence of a significant inflammatory response.
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Mindfulness Based Stress Reduction (MBSR) research over 30 years has explored its potential benefits for mood disorders, chronic medical illness, and pain as well as mental and physical health for non-medical populations.
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Weight loss and weight maintenance are often difficult to achieve. Although exercise is recommended as one of the mainstays of treatment, many overweight people have difficulty finding a feasible and enjoyable form of exercise.