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This monograph provides an overview of allergic disorders and reviews the current understanding of the mechanism of the allergic response. Due to the extensive nature of the topic, the discussion has been limited to systemic reactions eliciting an IgE-mediated response. Further, the intimate relationship between organs involved is reviewed, particularly the relationship between allergic rhinitis and asthma.
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The FDA has approved a new drug for the management of alcohol dependence.
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Studies on HCV infection resolution show that PBMC HCV-RNA may remain, despite clearance of the virus from plasma.
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Headaches commonly attributed to sinus are very likely to be migraines.
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A new and as yet unpublished study has raised increased concern about the relationship between rofecoxib (Vioxx), Mercks blockbuster COX-2 inhibitor, and cardiovascular events.
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The ECG in the Figure was obtained from a 23-year-old male who presented with a several day history of atypical chest pain. His ECG was interpreted as consistent with an early repolarization variant. Should anything else be considered in the differential?
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The diagnosis of hyperhidrosis, or excessive sweating, is achieved by clinical inquiry rather than laboratory testing, though quantitative metrics are available for clinical research.
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Neck pain is common among the general population. Half of those patients who report this symptom have persistent complaints at 1 year. At particular risk for persistent neck pain are those ages 45-59 years, those with chronic low back pain, and patients who ride their bicycles regularly.
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Survival benefits in the first year after acute MI, in patients 65 years or older, seem to differ according to specific ACE I prescribed.