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FDA-approved pharmacologic treatments for fibromyalgia (FIB) include duloxetine, milnacipran, and pregabalin. Although each of these agents has shown both statistically significant and clinically relevant impact, few patients are relieved of all problematic symptoms. Hence, additional treatment paths for FIB are sought.
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A new emergency contraceptive has been approved by the FDA that is effective up to 5 days after unprotected intercourse. Ulipristal acetate is a selective progesterone receptor modulator with partial agonist and partial antagonistic effects. It is licensed from Laboratoire HRA Pharma in France and marketed by Watson Pharma as Ella™.
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Calcium supplementation without vitamin D supplementation is associated with an increased risk of myocardial infarction.
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HDL-cholesterol concentrations are not predictive of residual vascular risk among patients treated with potent statin therapy who have attained very low concentrations of LDL-cholesterol.
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The ECG above was obtained from an 87-year-old woman in for her first doctor visit in several years. She reports no recent symptoms. She is on no cardioactive medications. What are your concerns?
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A Canadian study reveals that while a majority of elderly patients undergoing hemiarthroplasty did not receive home care upon discharge, those that did had longer short-term survival.
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A third inhaled corticosteroid and long-acting beta-agonist combination has been approved by the FDA, joining currently marked combinations fluticasone/salmeterol (Advair Diskus®) and budesonide/formoterol (Symbicort®). Mometasone furoate and formoterol fumarate is marketed by Schering as Dulera®
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Dietary pattern analysis of elderly subjects followed over at least 4 years showed lower risk for developing Alzheimer's disease when there was higher intake of nuts, fish, tomatoes, poultry, salad dressing, cruciferous vegetables, fruits, and dark and green leafy vegetables, along with lower intake of high-fat diary products, red meat, organ meat, and butter.
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Although there are few studies that specifically look at the elderly, this review provides useful information on the diagnosis and treatment of acute exacerbation of COPD and chronic bronchitis.
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In women, insomnia was not associated with increased risk of death, regardless of sleep duration. In men, mortality risk was significantly increased only in insomniacs who slept less than 6 hours and who were diabetic or hypertensive at baseline.