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The authors concluded that in patients with AF, decreasing GFR was associated with a higher risk of cardiovascular events and bleeding. Apixaban as compared to warfarin reduced these risks regardless of renal function, with the greatest benefit seen in reducing major bleeding in those with impaired renal function.
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A selective estrogen receptor modulator (SERM), also known as an estrogen agonist/antagonist, has been approved by the FDA for the treatment of dyspareunia (painful intercourse) in postmenopausal women. Ospemifene is manufactured by Penn Pharmaceuticals Services Ltd. and marketed by Shionogi Inc. as Osphena.
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The injection of a dextrose solution in and around the knee (prolotherapy) is an alternative treatment for the pain of knee osteoarthritis. A randomized, controlled trial shows that prolotherapy is effective for long-term control of knee pain and improvement in knee function.
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Five days of steroid treatment was as effective as 14 days of treatment in preventing repeat exacerbations of COPD in patients presenting to the emergency department with COPD exacerbations.
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A More Effective Regimen for H. pylori Eradication; Uric Acid: How Much of a Bad Guy?; The Word GPR40 Modulator May Soon be Entering Our Vocabulary
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A prospective study on Epstein-Barr virus seronegative college freshmen found that primary infection was symptomatic in 89% of cases. Kissing was the primary risk factor for infection, and blood viral load, CD8+ lymphocytosis, and IL-6 levels correlated with disease severity.
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ietary modifications among other lifestyle changes prevent development of type 2 diabetes.
hole fruits contain more phytochemicals, fiber, and antioxidants, and thus more health benefits, than fruit juice.
lueberries significantly decrease the risk of developing type 2 diabetes.
ruit juice significantly increases the risk of developing type 2 diabetes.