-
The FDA has approved an extended-release, once-daily, dipeptidyl-4 (DPP-4) inhibitor in combination with metformin for adults with type 2 diabetes. Janumet XR combines sitagliptin and metformin. The new combination is the second such product joining Kombiglyze XR, which combines saxagliptin and metformin. Janumet XR is marketed by Merck & Co., Inc.
-
The choice of if and when to employ pharmacotherapy in the management of Alzheimer's disease (AD) is not an easy one.
-
Two large, well-known, U.S. prospective cohort studies, the Nurses' Health Study and the Health Professionals Follow-up Study, evaluated both sugar-sweetened and diet (low-calorie, also called artificially sweetened) soda consumption over 20 years and found one or more daily servings to be associated with a significantly higher risk of stroke.
-
In this study of patients imaged with CT angiography, finding of the presence of diagonal earlobe creases was independently and significantly associated with increased prevalence, extent, and severity of coronary artery disease.
-
Dangers of antibiotics are well known and recent research brings to light new dangers of commonly used medications. Five days of azithromycin results in 47 additional deaths from cardiovascular disease compared with amoxicillin and no antibiotic. One out of 2500 patients treated with a fluoroquinolone (ciprofloxacin, levofloxacin, and norfloxacin) suffer a retinal detachment. These antibiotics should be used only when there is a clear clinical need and with caution.
-
-
Unless a dramatic demographic shift occurs, approximately one in four of us will reside in a long-term care facility (LTCF) during our lifetime. Among LTCF residents, 30-50% of antibiotic utilization is for urinary tract infections (UTIs), resulting in substantial expense, adverse drug reactions, and ever-growing populations of resistant bacteria.
-
-
An 8-week yoga training program improved balance performance measures and reduced fear of falling in adult patients with a history of stroke.
-
It is proverbial in modern life that the health benefits claimed initially for foods and natural products will eventually prove to be overly optimistic (for example, oat bran and dark chocolate), or at least subject to balancing against potential harms (for example, bacterial contamination of fresh produce and unpasteurized juices). Such cautionary examples should not and usually do not prevent appropriate use of such items, provided that we have a realistic idea of what they can do and what their attendant harms may be.
