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New guidelines from the ACP suggest that rather than universal screening, women aged 40-49 should be assessed for individual risk of breast cancer, and should be informed of the potential benefits and harms of screening mammography, then selectively screened based on the findings.
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For persistent asthma, clinical guidelines recommend low-dose inhaled corticosteroids (LDIC) as initial maintenance therapy.
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In a small sample of adults who were healthy except for elevated blood pressure, addition of small amounts of dark chocolate to their usual diet resulted in lowered blood pressure and improved formation of vasodilative nitric oxide.
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Use of a symptom-driven dose of a combined steroid and albuterol inhaler was equally effective for mild persistent asthma compared to a twice daily steroid inhaler, and resulted in a smaller cumulative dose of inhaled steroids in the six month study period.
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In patients with suspected pulmonary tuberculosis who are unable to expectorate sputum, culture of 3 induced sputum samples, all collected on the same day, is an effective and efficient means of diagnosis.
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A prodrug of dextroamphetamine has been approved by the FDA for the treatment of attention-deficit/hyperactivity disorder (ADHD). Lisdexamfetamine is the d-amphetamine covalently bound to l-lysine. It is marketed by Shire US Inc as Vyvanse.
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Statin-treated patients who developed symptoms of myopathy should be treated with at least 100 mg daily of coenzyme Q10 for a minimum of 30 days (assuming CPK values and/or other liver function tests are not abnormal) before discontinuing statin therapy.
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The FDA has approved the first continuous, low dose, oral contraceptive for the prevention of pregnancy.
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Almost 90% of persons with type 2 diabetes (DM2) are overweight. Weight loss in DM2 consistently results in meaningful favorable changes in lipids, glucose, and insulin resistance, so the clinical community embraces tools to enhance weight loss in this population.
