Studies on the effects of pomegranate juice on CYP-mediated drug metabolism have yielded inconsistent results, but this recently published case report raises the specter of interaction between the juice and warfarin, a drug whose narrow therapeutic window and potential for significant complications are well known.
Imaging procedures are an important source of exposure to ionizing radiation in the United States and can result in high cumulative effective doses of radiation.
Vitamin C supplementation prevents increases in endurance capacity and maximum oxygen uptake, because it prevents some cellular adaptations to exercise.
Internet-based self-management resulted in improvements in asthma control and lung function with resultant increases in the number of symptom-free days. However, this did not significantly reduce exacerbation rates.
The second competitive, reversible dipeptidyl peptidase-4 (DPP-4) inhibitor has been approved by the FDA for the treatment type 2 diabetes mellitus.
Most colorectal cancers overexpress cyclo-oxygenase 2 (COX-2). Primary prevention with aspirin (ASA) is associated with reduced risk for colon cancer and colonic adenoma.
A non-iodinated derivative of amiodarone has been approved by the FDA for the treatment of atrial fibrillation and atrial flutter.
Tamoxifen and CYP2D6 inhibitors, FDA Actions, and FDA Warnings.