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Golimumab is indicated for the treatment of adults with moderately to severely active rheumatoid arthritis in combination with methotrexate (MTX), active psoriatic arthritis, and active ankylosing spondylitis with or without methotrexate or other non-biologic disease-modifying antirheumatic drug (DMARD).
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Although osteoporosis and osteopenia occur in persons of all ages, they most commonly affect institutionalized long-term care and community-dwelling elderly patients, the same population segments with the highest risk of tooth loss and periodontal disease.
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Regular consumption of substantial amounts of cranberry juice or sauce by patients stabilized on warfarin (Coumadin, Jantoven) has been implicated in several cases of otherwise inexplicable increases of International Normalized Ratio (INR), including a few with serious hemorrhages.
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Results of this small pilot trial suggest that acupuncture analgesia in the ED may be both effective in managing pain associated with minor extremity trauma as well as feasible. While the conclusions are welcome, they serve more to advance the notion that further study is warranted than to promote application of acupuncture in the acute setting.
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Results of this large, retrospective cohort investigation suggest that cumulative significant childhood stress and trauma contribute to development of systemic inflammation and autoimmune disease during adulthood.
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This report describes the unfortunate case of a woman who unwittingly exposed herself to moderately high-dose zinc supplementation for a period of years without attendant copper supplementation, ultimately suffering irreversible neurologic consequences due to copper deficiency.
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In the United States, approximately $23 billion are spent on multivitamins yearly. At least half of all Americans take some kind of supplement, the majority of which are multivitamin/minerals.
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In patients with stable type 2 diabetes, a low-glycemic index diet for six months gave a modestly better reduction in HbA1c concentration compared to a high-cereal fiber diet. A high withdrawal rate raises questions about the practicality of adhering to the diet.
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The NIH has identified a range of Challenge Areas that focus on specific knowledge gaps, scientific opportunities, new technologies, data generation, or research methods that would benefit from an influx of funds to quickly advance the area in significant ways. Each NIH institute, center, and office - including the National Center for Complementary and Alternative Medicine (NCCAM) - has selected specific Challenge Topics within the broad Challenge Areas related to its mission.
