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With the introduction of genetic testing that is increasingly affordable, more patients are approaching their health care providers about such testing or with results from their direct-to-consumer genetic tests. Research findings linking MTHFR gene polymorphisms and disease risk have been conflicting. This has led to challenges as far as interpreting such data.
A survey of U.S. primary care physicians found that although most recommend weight loss to their obese patients, they do not utilize current evidence-based recommendations, and they underestimate the therapeutic effects of small weight losses.
Brown adipose tissue is involved in temperature regulation, and relates to metabolic rate and body mass index. Its activity appears to be reduced in people who are obese.
Patients with chronic heart failure (CHF) report progressively worse dyspnea with exercise, ranging from Class I NYHA (symptoms only present with strenuous exercise) to Class IV NYHA (symptoms present with any activity, even at rest).
Despite a clear-cut association between asthma and gastroesophageal reflux, aggressive PPI treatment had no clinical effect on poorly controlled asthma.
Insomnia persists.