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Dapagliflozin can be prescribed to lower the risk of hospitalization for heart failure in adults with chronic kidney disease at risk for progression, end-stage kidney disease, cardiovascular death, and sustained estimated glomerular filtration rate decline.
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Loneliness appears to be an independent risk factor for type 2 diabetes, although further research to identify the causal relationship between loneliness and type 2 diabetes development is needed.
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Researchers found extending the upper limit of HPV vaccination to age 30 to 45 years is not cost-effective.
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The CDC and the American College of Physicians have provided advice on the best practice regarding the duration of antibiotic therapy for several common infections.
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Party Affiliation and Social Distancing; Ethnicity and Occupation as Risk Factors for COVID Infection
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Cytomegalovirus (CMV) viremia emerges in the majority of CMV seronegative recipients of liver transplants from CMV seropositive donors, most often within the first post-transplant month. The only independent risk factor identified was increasing donor age.
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A review of 24 cases of Nocardia brain abscess, two-fifths of which occurred in apparently non-immunocompromised hosts, had variable outcomes, but antibiotic therapy was effective in most.
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In addition to identifying several patient risk factors for contamination of blood culture specimens, the authors also highlighted various adverse clinical and financial adverse effects.
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In the United States, rapid diagnostic testing for panels of potential gastrointestinal pathogens in children increases the yield of identifying rare pathogens, but, overall, does not change length of stay for hospitalized patients or reduce hospital charges.
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In a retrospective study, the investigators failed to find evidence of benefit of adjunctive rifampin therapy in patients with staphylococcal prosthetic valve endocarditis.