Infectious Disease
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Treatment of Presumed Urinary Tract Infection in Afebrile Males: How Long Is Long Enough?
Symptom resolution after seven days of antibiotic therapy in afebrile males with presumed urinary tract infection was not inferior to 14 days of therapy.
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COVID-19: Effective Post-Exposure Prophylaxis
Subcutaneous administration of a combination of anti-SARS-COV-2 antibodies effectively prevented COVID-19 in most household contacts of cases.
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Updated Sexually Transmitted Infection Guidelines
The Centers for Disease Control and Prevention has updated their recommendations for the treatment of several sexually transmitted infections, including gonorrhea, trichomoniasis, bacterial vaginosis, pelvic inflammatory disease, and those due to Chlamydia trachomatis and Mycoplasma genitalium.
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Neutrophil Extracellular Traps and COVID-19
Neutrophil extracellular traps (NETs) contribute to immune-mediated inflammation and thrombosis. Donor neutrophils were stimulated with plasma from patients hospitalized with COVID-19. R406 (metabolically active component of fostamatinib) abrogated release of NETs in vitro.
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Children Hospitalized with SARS-CoV-2
Two recently published studies give a clear, consistent finding: About three-fourths of children hospitalized with SARS-CoV-2 do not have severe COVID-19-related illness but are merely identified as infected when subjected to screening tests. Surveys reporting the number or incidence of SARS-CoV-2-infected hospitalized children likely overestimate the actual burden of disease.
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Medical Groups Back Youth Right to Consent
National organizations filed amicus briefs in two federal cases centered on a law enacted in Washington, DC. -
Survey: More Education Could Boost COVID-19 Vaccination Rates Among Youth
Adolescents and their parents are interested in taking the COVID-19 vaccine; more education and other developments could sway even more, according to the results of a survey. Respondents indicated more information on safety and efficacy for adolescents was one of the top factors that would increase the likelihood of taking the vaccine. They also said primary care providers and health officials were their most trusted sources for vaccine information. -
Complicated Ethics of Adolescent Children Self-Consenting for Vaccines
Parental rights issues often are asserted, but at the same time, society has a stake in protecting children from harm, including medical neglect. -
Many Ethical Considerations for MDs if Patient Is Unvaccinated
Beyond the ethical questions, there are logistics, privacy, and even equity concerns to consider. -
C. auris Can Be Stopped, but Not Easily
A superbug that can become pan-resistant to fungal drugs, Candida auris first was reported in the United States in 2013 and continues to spread and cause hospital outbreaks.