Infectious Disease
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IP Cuts SSIs by 55%, Saves a Net $805,000
A hospital saved a tidy sum and left 10 patients much happier — those who did not have surgical site infections (SSIs), as predicted by the SSI rate prior to an intervention that revamped the patient preparation protocol. -
CDC: Resistance Emerging to Last-Line Carbapenem Drugs
Carbapenems are a last-line antibiotic, one of the final weapons in the formulary against multidrug-resistant bacteria. But the ever-evolving bugs are starting to solve this drug class and have found an ingenious way to do it — genetic transfer of resistant properties to another Gram-negative bacterium.
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Bacteriophages: Strange Viruses that Eat Bacteria for Breakfast
For an American couple, it began with a dream trip to the Valley of the Kings in Egypt. It turned into the curse of the pharaohs. The husband developed a pan-resistant Gram-negative infection that turned septic.
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Game Changer: COVID-19 Delta Variant Breaks Through in Provincetown
The Provincetown, MA, COVID-19 outbreak in July made headlines because hundreds of fully vaccinated people had breakthrough infections. The critical question is whether the Provincetown outbreak is more of an outlier, or is it a harbinger of the kind of outbreaks and vaccine breakthroughs we may see more often with the highly transmissible delta variant?
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Pediatric Malaria
Malaria is present in all continents except Antarctica and has led to significant human illness and death. Children account for the majority of malaria deaths globally, making malaria a significant contributor to childhood mortality worldwide. Malaria is a mandatory consideration for children with fever who are returned travelers, since the disease process can lead to significant mortality and rapid clinical decline. The authors provide an update and current state of care for malaria in the pediatric population. -
Finerenone Tablets (Kerendia)
Finerenone can be prescribed to lower the risk of sustained estimated glomerular filtration rate decline, cardiovascular death, non-fatal myocardial infarction, end-stage kidney disease, and hospitalization from heart failure in adults with chronic kidney disease associated with type 2 diabetes. -
Association of Sleepwalking and REM Sleep Behavior Disorder in Men with Parkinson’s
In this retrospective, cross-sectional study of men, both sleepwalking and rapid eye movement sleep behavior disorder were associated with the development of Parkinson’s disease. -
Anticholinergic Use for Three Months or More Increases Dementia Risk
There is a significant increase in dementia risk associated with the use of anticholinergic medications for three months or longer. -
A Probiotic May Cause Sepsis and Death
Saccharomyces boulardii is a probiotic yeast that may cause fungemia and other fungal infections. -
Common Herbal and Dietary Supplements for Patients with Type 2 Diabetes: Part 2
The authors review chromium, cinnamon, fenugreek, garlic, and Gymnema sylvestre as complementary and alternative medicine supplements for managing type 2 diabetes.