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The comments below are in response to the article "Early Referral of the Chronic Kidney Disease Patient is Good Practice," by Rahul Gupta, MD, MPH, FACP, which appeared in the Jan. 29, 2012, issue. The comments from two of our editorial board members represent somewhat differing perspectives on the role of the primary care clinician in the management of chronic kidney disease. Obviously there is great opportunity for improvement in this area and those of us in primary care are in a unique position to optimize outcomes. Stephen Brunton, MD, Editor
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In a cross-sectional sample of postmenopausal women not using hormonal therapy, higher serum levels of estrogen were associated with improved semantic memory and verbal episodic memory abilities.
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In a double-blind, randomized clinical trial, amoxicillin therapy did not improve outcomes in patients with clinically diagnosed acute rhinosinusitis.
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The authors concluded that ECG LVH and LVH with strain were independently predictive of cardiovascular events, including aortic valve replacement in asymptomatic patients with moderate aortic stenosis.
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The FDA has approved a new pancreatic enzyme preparation for the treatment of pancreatic insufficiency. Pancrelipase contains porcine derived lipases, proteases, and amylases. It is marketed by Aptalis Pharma U.S. Inc. as Viokace.
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In this issue: Azithromycin and cardiac risk; warfarin and heart failure; aspirin and VTE; effectiveness of long-acting contraceptives; and FDA actions.
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HIV Risk Triplesin Women with an STD
Mlisana K, et al. Symptomatic vaginal discharge is a poor predictor of sexually transmitted infections and genital tract inflammation in high-risk women in South Africa. J Infect Dis 2012;206:6-14.
Classical sexually transmitted diseases drive the spread of HIV-1: Back to the future. J Infect Dis 2012;206:1-2.
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Jain and colleagues at the U.S. CDC evaluated the characteristics of 195 hospitalized patients with laboratory-confirmed influenza influenza A pdm09 (pH1N1) infection who had pneumonia, comparing them to hospitalized flu patients without pneumonia.