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Infectious Disease

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Articles

  • Full June 2005 Issue in PDF

  • Pharmacology Watch: Is Nesiritide Associated with a Higher Death Rate?

    Nesiritide, Scios' intravenous recombinant form of human B-type naturetic peptide, has been widely used for the treatment of congestive heart failure in hospitalized patients.
  • Pharmacology Watch: The FDA Pulls Another COX-2 Inhibitor Off the Market

    Is Holding NSAIDs Prior to Surgery Rational?; Low-Dose Aspirin: Men vs Women; FDA Actions
  • Updates By Carol A. Kemper

    In vitro resistance to daptomycin associated with clinical failure during treatment for MRSA infection has not been well documented. In vitro resistance to daptomycin is uncommon, de novo-resistant clinical isolates have not yet been reported, and the incidence of resistance, occurring during treatment is believed to be very low. The mechanism of resistance is not even known.
  • Efficacy of Oral Cholera Vaccine

    This article evaluates a mass immunization program with recombinant cholera-toxin B subunit, killed whole cell (rBS-WC) cholera vaccine in Beira, Mozambique, a city where seroprevalence of HIV infection is 20-30%.
  • Marburg Virus Infection

    In 1967, in marburg, a medieval university town north of Frankfurt, Germany, on the Lahn River, several employees of a Behringwerke AG, a manufacturer of vaccines, were hospitalized at the University Medical Clinic with a severe influenza-like illness.
  • Infection and Anemia

    Anemia of Chronic Disease (ACD) is a common disorder occurring in patients with acute and chronic inflammatory conditions. ACD is associated with infectious diseases, as well as with malignancies and autoimmune disorders. The pathophysiology of ACD involves abnormalities in iron homeostasis, impaired erythropoiesis, and blunted responses to erythropoietin, brought about by mediators of inflammation such as TNF-alpha, interferon-gamma, and interleukins.
  • Full May 2005 Issue in PDF

  • Clinical Briefs in Primary Care supplement

  • TB, BCG, PPD, and Travelers

    The interpretation of tuberculin skin tests (tst) is challenging and controversial, especially in the face of previously administered BCG vaccine. In Switzerland, a country where TB infection is not common but where BCG had previously been routinely given, Zysset and colleagues prospectively evaluated 2- step (second test done 8-15 days after the first for possible booster effect) TST results in 5117 hospital employees, in view of potential risk factors for TB infection.