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An outbreak of highly drug-resistant S. enterica Serotype Typhimurium which was resistant to all drugs tested was first identified in 2 young boys in 2004 in Minnesota and North Carolina who had been in contact with pet mice.
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Treatment of chronic Hepatitis B is directed at suppressing viral replication, reducing hepatitis (necroinflammatory) activity, slowing progression of fibrotic disease, inducing loss of HBeAg with seroconversion to anti-HBe, and rendering patients noninfectious.
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Uk-427,857 (Maraviroc) is an investigational small-molecule HIV entry inhibitor that binds to the CCR5 chemokine receptor on the surface of T-cells. This chemokine receptor is normally the receptor for the chemokines MIP-1 alpha and RANTES.
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Male sexual partners of women with vaginal trichomoniasis were tested, using urethral and urine culture, as well as urine polymerase chain reaction (PCR), for evidence of infection with this flagellated protozoan.
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Pronovost and colleagues conducted a multi-hospital cohort study aimed at reducing the rate of catheter-related bloodstream infections (CRBSIs) in ICUs. The intervention focused on increasing adherence to evidence-based CDC recommendations for catheter insertion.
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In a multicenter international open-label study, patients with proven or probable invasive aspergillosis (IA) that was refractory to standard antifungal therapy or who were intolerant to such therapy were treated with posaconazole in a total daily amount of 800 mg administered in divided doses.
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Searching Google yielded a correct diagnosis in greater than half of cases.
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The Finnish Diabetes Prevention Study (FDPS) demonstrated that a program of diet and exercise was capable of reducing the incidence of diabetes by approximately 60% in persons with impaired fasting glucose (IFG) or impaired glucose tolerance (IGT), compared to placebo.
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The FDA has approved a new atypical antipsychotic agent. Paliperidone is the active metabolite of risperidone. The drug is formulated in an osmotic drug delivery system (OROS) developed by ALZA.