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SSRIs are associated with a low rate of birth defects according to 2 new studies in the New England Journal of Medicine.
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A prodrug of dextroamphetamine has been approved by the FDA for the treatment of attention-deficit/hyperactivity disorder (ADHD). Lisdexamfetamine is the d-amphetamine covalently bound to l-lysine. It is marketed by Shire US Inc as Vyvanse.
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In patients with suspected pulmonary tuberculosis who are unable to expectorate sputum, culture of 3 induced sputum samples, all collected on the same day, is an effective and efficient means of diagnosis.
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Use of a symptom-driven dose of a combined steroid and albuterol inhaler was equally effective for mild persistent asthma compared to a twice daily steroid inhaler, and resulted in a smaller cumulative dose of inhaled steroids in the six month study period.
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In a small sample of adults who were healthy except for elevated blood pressure, addition of small amounts of dark chocolate to their usual diet resulted in lowered blood pressure and improved formation of vasodilative nitric oxide.
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For persistent asthma, clinical guidelines recommend low-dose inhaled corticosteroids (LDIC) as initial maintenance therapy.
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New guidelines from the ACP suggest that rather than universal screening, women aged 40-49 should be assessed for individual risk of breast cancer, and should be informed of the potential benefits and harms of screening mammography, then selectively screened based on the findings.