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In this issue: Aspirin dose and cardioprotection; uncovering modafinil's abuse potential; proton-pump inhibitors and clopidogrel; FDA actions.
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Much is being written about the transmission of MRSA between animals and humans. These investigators explored this problem from another angle, examining colonization of pet therapy dogs with MRSA, VRE, and C. difficile during visits to acute and long-term care facilities.
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Extended spectrum β-lactamase (ESBL)-producing Escherichia coli has emerged as an increasingly common cause of community-acquired urinary tract infections (UTIs).
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These guidelines were last updated for adults in 2002 and for adolescents in 2004. The document (available in pdf format through the link above) is a 209-page file containing 1,391 references which update current recommendations for the prophylaxis and treatment of HIV-related OIs.
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In vitro treatment of clinical isolates and isogenic strains of E. coli O157:H7 with ciprofloxacin increased the production of Stx2 (as measured by ELISA) via phage induction but did not increase the production of Stx1.
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A new transdermal formulation of oxybutynin has been approved for the treatment of overactive bladder. Oxybutynin gel is marketed by Watson Pharmaceuticals as Gelniqueä.
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Compared with invasive coronary angiography, coronary computed tomographic angiography demonstrated high diagnostic accuracy for detection of obstructive coronary stenosis and a 99% negative predictive value.
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Oral antibiotics were not found to be inferior to intravenous antibiotics in the treatment of clinically diagnosed acute diverticulitis.
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Use of statins as primary prevention in healthy people with elevated high-sensitivity C-reactive protein without hyperlipidemia may reduce the incidence of major cardiovascular events.
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