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In the intensifying effort to immunize more health care workers against influenza, a precedent-setting battle is taking shape at Virginia Mason Medical Center (VMMC) in Seattle. In what is thought to be the first hospital in the United States to take such action, Virginia Mason officials have mandated annual flu shots as a condition of health care employment.
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Reports to the federal vaccine adverse event reporting system (VAERS) in the first two seasons of trivalent live, attenuated influenza vaccine (LAIV-T) use did not identify any unexpected serious risks with the vaccine when used according to approved indications, the authors report.
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Synopsis: Three ICU patients receiving Saccharomyces boulardii (cerevisiae) therapy for treatment of Clostridium difficile colitis experienced fungemia. Review of 60 cases of S. cerevisiae fungemia reported in the literature found that risk factors included presence of a central venous catheter, intravenous or enteral alimentation, and receipt of S. cerevisiae as a probiotic.
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Clostridium difficile continues to emerge in a more pathogenic form with a new epidemiological profile. Particularly disturbing are new reports in four states of infections in patients previously thought to be at low risk for C. diff.
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Health care workers are more likely to receive post-exposure treatment after a bloodborne pathogen exposure than they were 10 years ago, but management of their regimens still needs improvement, according to the Centers for Disease Control and Prevention (CDC) in Atlanta.
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Failure of initial antibiotic therapy is a well-known cause of morbidity and mortality in infections such as ventilator-associated pneumonia. However, the damage doesnt stop there. Inappropriate antibiotic empiric therapy can be a surprisingly costly and sometimes deadly consequence even for less serious infections.
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ADEP I-6 have a complex ring structure. ADEP-I is the primary natural product (factor A). ADEP-1 has congeners that have been optimized for antibacterial activity, with the addition of 2 fluorides, to produce a difluoronated phenylalanine side chain.
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Synopsis: Investigators reported finding the presence of a metallo-â-lactamase gene mediating resistance to multiple â-lactam antibiotics, including carbapenems, among multiple species of Gram-negative pathogens isolated from a single hospital in Australia.