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The optimal time to initiate antiretroviral therapy (ARV) in chronically-infected asymptomatic patients is now felt to be when the CD4+ lymphocyte count falls to approximately 350 cells/uL, based on the probability of developing an AIDS-defining illness within a relatively short period of time, as shown in a meta-analysis of cohort studies.
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From July through November 2003, a rapidly growing non-tuberculous Mycobacterium was recovered in culture from 11 of 15 women with wound infections after breast surgery all but one involving silicon gel implants. Thirteen of the procedures were performed by a single surgeon; infection developed in 12 of 42 (28.6%) patients operated on by this individual.
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A prospective study of the immunogenicity and reactogenicity of one vs 2 doses of 2004-2005 trivalent influenza vaccine (TIV), in 5 8-year-old children, was conducted among 280 children who had not received TIV. Of these, 222 received 2 doses of TIV and had 3 blood samples. An additional 10 received 2 doses of TIV and were included in the safety analyses. The mean age of the 222 children was 6.5 years; 57% were male.
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Each year in the United States, a few isolated cases of plague are reported. This year, possibly because of increased spring rains leading to an increase in the rodent population, an unprecedented 13 cases of plagues have occurred in 4 states (New Mexico, California, Colorado, and Texas).
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While a matter of much concern and discussion in the United States, methicillin-resistant Staphylococcus aureus (MRSA) also is arising in some rather bizarre manifestations in Europe.
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Kansas City, KS. During May 1-Dec. 31, 2005, a total of 201 confirmed Shigella sonnei infections were reported among residents of Kansas City, KS. Median age of patients was 7 years (range: 1-70 years).
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The Centers for Disease Control and Prevention offers the following answers to some frequently asked questions about its new guidelines of HIV testing:
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